Treatment of experimentally induced bovine respiratory disease in young calves with a single administration of a combination of florfenicol and meloxicam

This study was designed to evaluate the efficacy of a new florfenicol/meloxicam combination (FMC) in calves with bovine respiratory disease. A total of 90 young calves were challenged via intratracheal deposition of 108 colony-forming units of Mannheimia haemolytica. Data for 84 calves demonstrating...

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Bibliographic Details
Published in:Veterinary record 2018-11, Vol.183 (17), p.535-535
Main Authors: Achard, Damien, Caruso-Vares, Agathe, Collin, Jean-François, McKelvie, Joanne, Reddick, David, Ramage, Cliff
Format: Article
Language:English
Subjects:
Animals
Antibiotics
Antimicrobial agents
Bacteria
bovine respiratory disease
Cattle
Fever
florfenicol
inflammation
meloxicam
Pathogens
Respiratory diseases
treatment
Veterinary medicine
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Summary:This study was designed to evaluate the efficacy of a new florfenicol/meloxicam combination (FMC) in calves with bovine respiratory disease. A total of 90 young calves were challenged via intratracheal deposition of 108 colony-forming units of Mannheimia haemolytica. Data for 84 calves demonstrating a rectal temperature (RT) above 39.5°C and a combined total clinical score (TCS) greater than or equal to 3 were included. Calves were then randomly allocated to one of the three study groups (FMC; florfenicol/flunixin combination (FFC); or saline) and promptly treated. RT and TCS of calves treated with an FMC or FFC were consistently lower than RT and TCS of calves belonging to the control group (P
ISSN:0042-4900
2042-7670
DOI:10.1136/vr.104795