Haematological and biochemical effects of polyphenolics in animal models

Polyphenols of natural and synthetic origin are exploited in tanning sector to convert putrescible skin/hide to non-putrescible leather. However, only 30–40% of the inputs have been taken up for processing, the remaining is released as unspent. The existing conventional wastewater treatment systems...

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Bibliographic Details
Published in:Chemosphere (Oxford) 2008-07, Vol.72 (9), p.1321-1326
Main Authors: Gnanamani, Arumugam, Sudha, Munusamy, Deepa, G., Sudha, M., Deivanai, K., Sadulla, S.
Format: Article
Language:English
Subjects:
Animal models
Animal, plant and microbial ecology
Animals
Applied ecology
Biological and medical sciences
Blood Cell Count
Blood Chemical Analysis
Blood Glucose - metabolism
Blood Urea Nitrogen
Cholesterol - blood
Creatinine - blood
Ecotoxicology, biological effects of pollution
Female
Flavonoids - blood
Flavonoids - toxicity
Fundamental and applied biological sciences. Psychology
General aspects
Haematological properties
Industrial Waste - analysis
Industry
Lipid profile
Phenols - blood
Phenols - toxicity
Polyphenolics
Polyphenols
Rats
Tanning
Tannins - blood
Tannins - toxicity
Triglycerides - blood
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Summary:Polyphenols of natural and synthetic origin are exploited in tanning sector to convert putrescible skin/hide to non-putrescible leather. However, only 30–40% of the inputs have been taken up for processing, the remaining is released as unspent. The existing conventional wastewater treatment systems are inefficient in removing or degrading these unspent polyphenols and thus detrimental to ecosystem. The present study demonstrates the evaluation of impact of both synthetic and natural polyphenols on biochemical and haematological properties of blood and serum in animal models. The results reveal that concentrations of polyphenols play a major role. At higher concentrations, irrespective of their nature, there was a marked change in the lipid profile (81% reduction), followed by insignificant change in glucose levels, RBC and WBC counts and other haematological parameters. At lower concentrations, no significant changes in the above said properties were observed.
ISSN:0045-6535
1879-1298
DOI:10.1016/j.chemosphere.2008.04.028