Cancers of the eye

Ocular cancers are unique among the diseases of the eye, threatening both vision and life. In most cases, the diagnosis can be made utilizing a careful clinical history and specialized ocular examination. Eye cancer diagnosis relies heavily on imaging techniques such as high-frequency ultrasound, fl...

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Bibliographic Details
Published in:Cancer and metastasis reviews 2018-12, Vol.37 (4), p.677-690
Main Authors: Maheshwari, Abhilasha, Finger, Paul T.
Format: Article
Language:English
Subjects:
Angiography
Basal cell carcinoma
Biomedical and Life Sciences
Biomedicine
Cancer
Cancer Research
Care and treatment
Chemotherapy
Complications
Computed tomography
CT imaging
Diagnosis
Enucleation
Eye
Eye diseases
Eyelid
Fluorescein
Intravenous administration
Lymphoma
Lymphomas
Magnetic resonance imaging
Medical imaging
Melanoma
Metastases
Metastasis
NMR
Nuclear magnetic resonance
Oncology
Optical Coherence Tomography
Radiation
Retina
Retinoblastoma
Skin cancer
Squamous cell carcinoma
Tomography
Tumors
Ultrasound
Vision
Vismodegib
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Summary:Ocular cancers are unique among the diseases of the eye, threatening both vision and life. In most cases, the diagnosis can be made utilizing a careful clinical history and specialized ocular examination. Eye cancer diagnosis relies heavily on imaging techniques such as high-frequency ultrasound, fluorescein angiography, anterior and posterior segment optical coherence tomography, computed tomography (CT), and magnetic resonance imaging (MRI). Once the diagnosis is established, treatment decisions depend on the tumor’s location, size, local extension, patterns of growth, and secondary complications. Treatment options include observation, local resection, chemotherapy (topical, intravenous, intra-arterial, or intravitreal), and radiation (ophthalmic plaque or external beam). Enucleation or exenteration is only employed if these eye- and vision-sparing treatments are not possible. The core of this comprehensive review is a consecutive series of the most common ocular tumor of each structure of the eye, anterior to posterior, including basal cell carcinoma of the eyelid, squamous conjunctival neoplasia, choroidal melanoma, retinoblastoma, ocular adnexal lymphoma, and metastatic orbital tumors.
ISSN:0167-7659
1573-7233
DOI:10.1007/s10555-018-9762-9