Immunogenicity of formaldehyde and binary ethylenimine inactivated infectious bursal disease virus in broiler chicks super()

Infectious bursal disease virus (IBDV) was inactivated by two different chemicals - formaldehyde and binary ethylenimine (BEI). Formaldehyde was used at 0.1% and 0.2%, while BEI was used at concentrations of 0.001 and 0.002 mol/L. These four vaccines were tested for their efficiency in generating hu...

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Bibliographic Details
Published in:Journal of Zhejiang University. B. Science 2006-08, Vol.7 (8)
Main Authors: Habib, Mudasser, Hussain, Iftikhar, Irshad, Hamid, Yang, Zong-Zhao, Shuai, Jiang-Bing, Chen, Ning
Format: Article
Language:English
Subjects:
Infectious bursal disease virus
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Summary:Infectious bursal disease virus (IBDV) was inactivated by two different chemicals - formaldehyde and binary ethylenimine (BEI). Formaldehyde was used at 0.1% and 0.2%, while BEI was used at concentrations of 0.001 and 0.002 mol/L. These four vaccines were tested for their efficiency in generating humoral immune response in different groups of broiler chicks. Both BEI-inactivated vaccines gave relatively higher antibody titers and were almost twice as efficient as formaldehyde-inactivated ones.
ISSN:1673-1581
DOI:10.1631/jzus.2006.B0660