An updated meta-analysis of transanal drainage tube for prevention of anastomotic leak in anterior resection for rectal cancer

Anastomotic leakage (AL) is one of the most serious complications after anterior resection for rectal cancer. Transanal drainage tube (TDT) placement is widely used to reduce AL, but its efficacy remains controversial. We performed a meta-analysis to evaluate the effectiveness of TDT for prevention...

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Bibliographic Details
Published in:Surgical oncology 2018-09, Vol.27 (3), p.333-340
Main Authors: Chen, Hong, Cai, Hong-Ke, Tang, Yun-Hao
Format: Article
Language:English
Subjects:
Anal Canal - surgery
Anastomotic Leak - etiology
Anastomotic Leak - prevention & control
Anastomotic leakage
Anterior resection
Bleeding
Cancer
Colorectal cancer
Complications
Control methods
Digestive System Surgical Procedures - adverse effects
DNA nucleotidylexotransferase
Drainage - methods
Gender
Humans
Meta-analysis
Mortality
Ostomy
Placement
Postoperative Complications - prevention & control
Prevention
Rectal Neoplasms - surgery
Rectum
Studies
Surgery
Transanal drainage tube
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Summary:Anastomotic leakage (AL) is one of the most serious complications after anterior resection for rectal cancer. Transanal drainage tube (TDT) placement is widely used to reduce AL, but its efficacy remains controversial. We performed a meta-analysis to evaluate the effectiveness of TDT for prevention of AL, using updated evidence. Randomized controlled trials (RCTs) and cohort studies evaluating the effectiveness of TDT for prevention of AL after anterior resection for rectal cancer were identified by using a predefined search strategy. Meta-analysis was performed to estimate the pooled rates of AL, reoperation, anastomotic bleeding and mortality separately. One RCT and ten cohort studies which including 1170 cases with TDT and 1262 cases without TDT were considered eligible for inclusion. Meta-analysis showed that the TDT group was associated with a significant lower rates of AL (RR: 0.42, 95% CI: 0.31–0.58, P 
ISSN:0960-7404
1879-3320
DOI:10.1016/j.suronc.2018.05.018