Real-world Experience of Using HLA-B27 Tag-single-nucleotide Polymorphism Assay to Screen for Axial Spondyloarthritis

We previously published an analytical validation of the tag-single-nucleotide polymorphism (SNP) assay in based on the initial identification of the tag-SNP by the International Genetics of Ankylosing Spondylitis Consortium. Our tag-SNP assay is much cheaper than the traditional HLA-B locus testing,...

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Bibliographic Details
Published in:Journal of rheumatology 2018-12, Vol.45 (12), p.1712-1712
Main Authors: Nguyen, Hai V, O'Rielly, Darren D, Rahman, Proton
Format: Article
Language:English
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Summary:We previously published an analytical validation of the tag-single-nucleotide polymorphism (SNP) assay in based on the initial identification of the tag-SNP by the International Genetics of Ankylosing Spondylitis Consortium. Our tag-SNP assay is much cheaper than the traditional HLA-B locus testing, and has been implemented at the Provincial Medical Genetics Laboratory of Eastern Health (St. John's, Newfoundland, Canada) since August 1, 2016. The data on the use of this assay have been systematically collected.
ISSN:0315-162X
1499-2752
DOI:10.3899/jrheum.180408