Divalproex for the treatment of geriatric bipolar disorder

Divalproex is now commonly used to treat bipolar disorder in older patients. However, it has yet to be systematically studied in this population. This report describes six older bipolar patients treated with divalproex. Of the six, five showed some improvement with divalproex alone or in combination...

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Bibliographic Details
Published in:International journal of geriatric psychiatry 1999-06, Vol.14 (6), p.494-496
Main Authors: Mordecai, Donald J., Sheikh, Javaid I., Glick, Ira D.
Format: Article
Language:English
Subjects:
Aged
Antimanic Agents - adverse effects
Antimanic Agents - therapeutic use
Biological and medical sciences
bipolar
Bipolar Disorder - drug therapy
divalproex
Drug Therapy, Combination
Female
geriatric
Humans
Male
Medical sciences
Middle Aged
Neuropharmacology
older
Pharmacology. Drug treatments
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
Psychology. Psychoanalysis. Psychiatry
Psychopharmacology
Retrospective Studies
Treatment Outcome
Valproic Acid - adverse effects
Valproic Acid - therapeutic use
Citations: Items that this one cites
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Description
Summary:Divalproex is now commonly used to treat bipolar disorder in older patients. However, it has yet to be systematically studied in this population. This report describes six older bipolar patients treated with divalproex. Of the six, five showed some improvement with divalproex alone or in combination with other agents. Clearly, a double‐blind, placebo‐controlled study is an important next step to assess this promising medication. Copyright © 1999 John Wiley & Sons, Ltd.
ISSN:0885-6230
1099-1166
DOI:10.1002/(SICI)1099-1166(199906)14:6<494::AID-GPS964>3.0.CO;2-9