Water-Based Black Phosphorus Hybrid Nanosheets as a Moldable Platform for Wound Healing Applications

Black phosphorus (BP) nanosheets with unique biocompatibility and superior optical performance have attracted enormous attention in material science. However, their instability and poor solution-processability severely limit their clinical applications. In this work, we demonstrate the use of silk f...

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Bibliographic Details
Published in:ACS applied materials & interfaces 2018-10, Vol.10 (41), p.35495-35502
Main Authors: Huang, Xiao-Wei, Wei, Jing-Jing, Zhang, Meng-Ya, Zhang, Xue-Liang, Yin, Xiao-Fei, Lu, Chun-Hua, Song, Ji-Bin, Bai, Shu-Meng, Yang, Huang-Hao
Format: Article
Language:English
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Summary:Black phosphorus (BP) nanosheets with unique biocompatibility and superior optical performance have attracted enormous attention in material science. However, their instability and poor solution-processability severely limit their clinical applications. In this work, we demonstrate the use of silk fibroin (SF) as an exfoliating agent to produce thin-layer BP nanosheets with long-term stability and facile solution-processability. Presence of SF prevents rapid oxidation and degradation of the resultant BP nanosheets, enhancing their performance in physiological environment. The SF-modified BP nanosheets exhibit subtle solution-processability and are fabricated into various BP-based material formats. As superior photothermal agents, BP-based wound dressings effectively prevent bacterial infection and promote wound repair. Therefore, this work opens new avenues for unlocking current challenges of BP nanosheet applications for practical biomedical purposes.
ISSN:1944-8244
1944-8252
DOI:10.1021/acsami.8b12523