Vitamin D supplementation does not improve plasma thiol/disulfide homeostasis

Background Impairment of thiol/disulfide homeostasis, as well as vitamin D deficiency, are responsible for the pathophysiology of many acute and chronic diseases. This study examined the relationship between thiol/disulfide homeostasis and vitamin D level and supplementation. Methods A total of 203...

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Bibliographic Details
Published in:Pediatrics international 2018-11, Vol.60 (11), p.1008-1013
Main Authors: Mertoglu, Cuma, Siranli, Gulsah, Topal, Ismail, Gok, Gamze, Erel, Ozcan
Format: Article
Language:English
Subjects:
25-Hydroxyvitamin D
Adolescent
Biomarkers - blood
Child
Child, Preschool
Children
Chronic illnesses
Dietary Supplements
Disulfides - blood
Female
healthy child
Homeostasis
Homeostasis - drug effects
Humans
Impairment
Infant
Infant, Newborn
Male
Oxidation
Oxidative stress
Pediatrics
Sulfhydryl Compounds - blood
Supplements
thiol/disulfide homeostasis
Treatment Outcome
Vitamin D
Vitamin D - pharmacology
Vitamin D - therapeutic use
Vitamin D Deficiency - blood
Vitamin D Deficiency - drug therapy
Vitamin D Deficiency - physiopathology
Vitamin deficiency
Vitamins - pharmacology
Vitamins - therapeutic use
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Summary:Background Impairment of thiol/disulfide homeostasis, as well as vitamin D deficiency, are responsible for the pathophysiology of many acute and chronic diseases. This study examined the relationship between thiol/disulfide homeostasis and vitamin D level and supplementation. Methods A total of 203 healthy children were included in the study. The participants were divided into four groups according to 25‐hydroxyvitamin D (25(OH)D) level: group 1, severe deficiency (
ISSN:1328-8067
1442-200X
DOI:10.1111/ped.13705