Combination of longitudinal pancreaticojejunostomy with coring-out of the pancreatic head (Frey procedure) and distal pancreatectomy for chronic pancreatitis

Purpose The Frey procedure is an effective surgery for chronic pancreatitis (CP) patients who have pancreatic head lesions with dilation of the main pancreatic duct. However, pancreatic tail lesions can cause relapsing pancreatitis after the procedure. Therefore, additional distal pancreatectomy (DP...

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Bibliographic Details
Published in:Surgery today (Tokyo, Japan) Japan), 2019-02, Vol.49 (2), p.137-142
Main Authors: Sato, Hideaki, Ishida, Masaharu, Motoi, Fuyuhiko, Sakata, Naoaki, Aoki, Takeshi, Suzuki, Hideyuki, Yamamura, Akihiro, Karasawa, Hideaki, Hata, Tatsuo, Ohtsuka, Hideo, Mizuma, Masamichi, Morikawa, Takanori, Hayashi, Hiroki, Nakagawa, Kei, Kamei, Takashi, Naitoh, Takeshi, Egawa, Shinichi, Unno, Michiaki
Format: Article
Language:English
Subjects:
Blood Loss, Surgical - statistics & numerical data
Diabetes Mellitus - epidemiology
Female
Humans
Incidence
Length of Stay
Male
Medicine
Medicine & Public Health
Middle Aged
Operative Time
Original Article
Pancreas - surgery
Pancreatectomy - methods
Pancreaticojejunostomy - methods
Pancreatitis, Chronic - surgery
Retrospective Studies
Surgery
Surgical Oncology
Treatment Outcome
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Summary:Purpose The Frey procedure is an effective surgery for chronic pancreatitis (CP) patients who have pancreatic head lesions with dilation of the main pancreatic duct. However, pancreatic tail lesions can cause relapsing pancreatitis after the procedure. Therefore, additional distal pancreatectomy (DP) might complement the therapeutic effect of the Frey procedure in controlling inflammation of the pancreatic tail. The Frey procedure with DP (Frey + DP) is indicated for inflammatory lesions in the pancreatic head and tail. In this study, we assessed the usefulness of Frey + DP using the retrospective clinical data of our cases. Methods The clinical outcomes were compared between CP patients who underwent the Frey procedure ( N  = 44) and Frey + DP ( N  = 13) from January 2005 to April 2016. Results Frey + DP showed similarly good therapeutic effects to the Frey procedure with regard to the postoperative stay, morbidity, mortality, pain relief and nutrition, although the Frey + DP had a longer operative time, more bleeding and higher incidence of diabetes mellitus than the Frey procedure because of the additional DP. One patient in the Frey group received additional DP because of recurrent pain due to the tail lesion. Conclusion Frey + DP can be a promising treatment for CP patients with pancreatic head and tail lesions.
ISSN:0941-1291
1436-2813
DOI:10.1007/s00595-018-1720-1