Defining antimicrobial resistance in cystic fibrosis

Antimicrobial resistance (AMR) can present significant challenges in the treatment of cystic fibrosis (CF) lung infections. In CF and other chronic diseases, AMR has a different profile and clinical consequences compared to acute infections and this requires different diagnostic and treatment approa...

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Bibliographic Details
Published in:Journal of cystic fibrosis 2018-11, Vol.17 (6), p.696-704
Main Authors: Kidd, Timothy J., Canton, Rafael, Ekkelenkamp, Miquel, Johansen, Helle Krogh, Gilligan, Peter, LiPuma, John J., Bell, Scott C., Elborn, J. Stuart, Flume, Patrick A., VanDevanter, Donald R., Waters, Valerie J.
Format: Article
Language:English
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Summary:Antimicrobial resistance (AMR) can present significant challenges in the treatment of cystic fibrosis (CF) lung infections. In CF and other chronic diseases, AMR has a different profile and clinical consequences compared to acute infections and this requires different diagnostic and treatment approaches. This review defines AMR, explains how it occurs, describes the methods used to measure AMR as well as their limitations, and concludes with future directions for research and development in the area of AMR in CF.
ISSN:1569-1993
1873-5010
DOI:10.1016/j.jcf.2018.08.014