One year in review 2018: systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a systemic autoimmune condition characterised by a wide spectrum of clinical manifestations, partly related to the disease itself, but also linked to its comorbidities and drugs adverse reactions. Following the previous annual reviews, we focused on new insights...

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Bibliographic Details
Published in:Clinical and experimental rheumatology 2018-09, Vol.36 (5), p.763-777
Main Authors: Di Battista, Marco, Marcucci, Elisa, Elefante, Elena, Tripoli, Alessandra, Governato, Gianmaria, Zucchi, Dina, Tani, Chiara, Alunno, Alessia
Format: Article
Language:English
Subjects:
Animals
Biomarkers - metabolism
Comorbidity
Disease Progression
Health Status
Humans
Immunosuppressive Agents - therapeutic use
Lupus Erythematosus, Systemic - diagnosis
Lupus Erythematosus, Systemic - drug therapy
Lupus Erythematosus, Systemic - epidemiology
Lupus Erythematosus, Systemic - immunology
Predictive Value of Tests
Quality of Life
Risk Factors
Treatment Outcome
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Summary:Systemic lupus erythematosus (SLE) is a systemic autoimmune condition characterised by a wide spectrum of clinical manifestations, partly related to the disease itself, but also linked to its comorbidities and drugs adverse reactions. Following the previous annual reviews, we focused on new insights in SLE clinical features, pathogenic pathways, biomarkers of specific organ involvement and therapeutic strategies. We finally concentrated on SLE aspects that could significantly influence patients' quality of life and that need to be investigated in detail through the development and validation of disease-specific patient-reported outcomes.
ISSN:0392-856X