Induction of neurogenesis in rat bone marrow mesenchymal stem cells using purine structure-based compounds

Rat bone marrow stem cells (rBMSCs) in the presence of chemical molecules were differentiated into neurons.

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Bibliographic Details
Published in:Molecular bioSystems 2009-01, Vol.5 (6), p.609-611
Main Authors: Cho, Mi Hee, Lee, Jung Hwa, Ahn, Hyun Hee, Lee, Ju Young, Kim, E Sle, Kang, Yun Mi, Min, Byoung Hyun, Kim, Jae Ho, Lee, Hai Bang, Kim, Moon Suk
Format: Article
Language:English
Subjects:
2',3'-Cyclic-Nucleotide Phosphodiesterases - metabolism
Animals
Basic Helix-Loop-Helix Transcription Factors - genetics
Bone Marrow Cells - cytology
Bone Marrow Cells - drug effects
Bone Marrow Cells - metabolism
Cell Differentiation - drug effects
Cell Survival - drug effects
Cells, Cultured
Gene Expression - drug effects
Glial Fibrillary Acidic Protein - genetics
Immunohistochemistry
Mesenchymal Stromal Cells - cytology
Mesenchymal Stromal Cells - drug effects
Mesenchymal Stromal Cells - metabolism
Molecular Structure
Myelin Basic Protein - genetics
Nerve Tissue Proteins - genetics
Neurofilament Proteins - genetics
Neurogenesis - drug effects
Neurons - cytology
Neurons - drug effects
Neurons - metabolism
Phosphopyruvate Hydratase - metabolism
Purines - chemistry
Purines - pharmacology
Rats
Reverse Transcriptase Polymerase Chain Reaction
Time Factors
Tretinoin - pharmacology
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Description
Summary:Rat bone marrow stem cells (rBMSCs) in the presence of chemical molecules were differentiated into neurons.
ISSN:1742-206X
1742-2051
DOI:10.1039/b905598n