Monoclonal antibodies in cancer immunotherapy

Nowadays, in cancer treatments, immunotherapy which can be classified as a cancer type specific therapy is more popular than non-specific therapy methods such as surgery, radiotherapy and chemotherapy. The main aim of immunotherapy is to enable patients’ immune system to target cancer cells and dest...

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Bibliographic Details
Published in:Molecular biology reports 2018-12, Vol.45 (6), p.2935-2940
Main Authors: Kimiz-Gebologlu, Ilgin, Gulce-Iz, Sultan, Biray-Avci, Cigir
Format: Article
Language:English
Subjects:
Animal Anatomy
Animal Biochemistry
Animals
Antibodies, Monoclonal - therapeutic use
Biomedical and Life Sciences
Cancer immunotherapy
Cancer therapies
Cancer vaccines
Cancer Vaccines - therapeutic use
Chemotherapy
Cytokines
Cytokines - therapeutic use
Histology
Humans
Immune system
Immunoglobulins
Immunologic Factors
Immunotherapy
Immunotherapy - methods
Immunotherapy, Adoptive
Life Sciences
Monoclonal antibodies
Morphology
Neoplasms - immunology
Neoplasms - therapy
Radiation therapy
Review
Surgery
Therapeutic applications
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Summary:Nowadays, in cancer treatments, immunotherapy which can be classified as a cancer type specific therapy is more popular than non-specific therapy methods such as surgery, radiotherapy and chemotherapy. The main aim of immunotherapy is to enable patients’ immune system to target cancer cells and destroy them. The mainly used treatment methods in cancer immunotherapy are cancer vaccines, adoptive cell therapy, cytokines and monoclonal antibodies. In this review, we discuss the immunotherapy approaches, especially monoclonal antibodies which are mostly used in cancer immunotherapy in clinical applications.
ISSN:0301-4851
1573-4978
DOI:10.1007/s11033-018-4427-x