What Proportion of Patients With Heart Failure and Left Ventricular Ejection Fraction 40% to 49% Fulfill the Criteria for Heart Failure With Mid-Range Ejection Fraction?

• Published in: The American journal of cardiology 2018-12, Vol.122 (12), p.2166-2167
• Main Authors: Webb, Jessica, Draper, Jane, S. Carr-White, Gerald
• Format: Article
• Language: English
• Subjects: Cardiology; Cardiovascular disease; Coronary artery disease; Ejection fraction; Guidelines; Heart; Heart diseases; Heart failure; Heart Failure - classification; Heart Failure - physiopathology; Humans; Patients; Population; Severity of Illness Index; Stroke Volume - physiology; Ventricle; Ventricular Function, Left - physiology
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/j.amjcard.2018.08.055

The European Society of Cardiology (ESC) updated guidelines introducing heart failure with mid-range ejection fraction (HFmrEF) were not validated before publication.1 The relative importance of stuctural heart disease or diastolic dysfunction in diagnosing HFmrEF is not known. [...]the exact prevalence remains unclear largely because different left ventricular ejection fraction (LVEF) have been used to define these “grey area” patients.2–4 The aim of this study was to establish the clinical impact of these guidelines. All consecutive patients admitted to hospital with heart failure (HF) were recruited over a 12-month period (follow-up 26.8 months, range 22.1 to 34.0). In total, 16 patients (11.3%) were admitted with HF, raised NTproBNP and LVEF 40% to 49% but with no evidence of diastolic dysfunction and/or structural heart disease, and so were not categorized as HFmrEF (Figure 1).