Metabolic clustering of a core collection of Indian ginseng Withania somnifera Dunal through DNA, isoenzyme, polypeptide and withanolide profile diversity

Withania somnifera is one of the most important medicinal plants of Ayurveda and finds extensive uses in Indian traditional herbal preparations. In this investigation, selected accessions of the plant were examined for diversity through RAPDs, isoenzymes, polypeptide polymorphism and withanolide pro...

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Bibliographic Details
Published in:Fitoterapia 2009-12, Vol.80 (8), p.496-505
Main Authors: Chaurasiya, Narayan D, Sangwan, Rajender S, Misra, Laxmi N., Tuli, Rakesh, Sangwan, Neelam S
Format: Article
Language:English
Subjects:
Ashwagandha
Genetic diversity
Isoenzymes
RAPD
Withania somnifera
Withanolide diversity
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Summary:Withania somnifera is one of the most important medicinal plants of Ayurveda and finds extensive uses in Indian traditional herbal preparations. In this investigation, selected accessions of the plant were examined for diversity through RAPDs, isoenzymes, polypeptide polymorphism and withanolide profiles. The accessions clustered together with respect to their characteristic profile of major withanolides and represented withaferin A, withanone, withanolide D or withanolide A rich groups. This level of phytochemical diversity as discrete chemotypes is widest and is being first ever documented to occur in Indian population of the plant. The novel and impressively wide phytochemical diversity as discrete chemotypes representing the presence and absence of withaferin A, withanone, withanolide A and withanolide D first ever been documented in Indian population of Withania somnifera (Ashwagandha). [Display omitted]
ISSN:0367-326X
DOI:10.1016/j.fitote.2009.06.012