A case of idiopathic portal hypertension associated with rheumatoid arthritis

A 53-year-old woman who had been diagnosed with rheumatoid arthritis was found to have thrombocytopenia, splenomegaly, and gastric varices. She was diagnosed as having idiopathic portal hypertension on the basis of liver biopsy and angiography. Treatment with prednisolone was not sufficiently effect...

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Bibliographic Details
Published in:Modern rheumatology 2006-04, Vol.16 (2), p.92-96
Main Authors: Sasajima, Tomomi, Suzuki, Tomohiro, Mori, Kenji, Ichii, Osamu, Tai, Mayumi, Ochiai, Hironobu, Ejiri, Yutaka, Watanabe, Hiroshi, Ohira, Hiromasa, Obara, Katsutoshi, Sato, Yukio
Format: Article
Language:English
Subjects:
Case studies
Hypertension
Medical diagnosis
Rheumatoid arthritis
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Summary:A 53-year-old woman who had been diagnosed with rheumatoid arthritis was found to have thrombocytopenia, splenomegaly, and gastric varices. She was diagnosed as having idiopathic portal hypertension on the basis of liver biopsy and angiography. Treatment with prednisolone was not sufficiently effective for thrombocytopenia. After transabdominal devascularization with splenectomy, thrombocytopenia subsided and gastric varices disappeared. In this case, the autoimmune mechanism as well as hypersplenism was suspected of being involved in the mechanism of thrombocytopenia. [PUBLICATION ABSTRACT]
ISSN:1439-7595
1439-7609
DOI:10.1007/s10165-006-0456-8