A pediatric patient with neuro-Behçet's disease

Behcet's disease is rare in childhood. We describe a 10-year-old boy with neuro-Behcet's disease (NB) who presented with fever, headache, vertigo, and hearing loss. An examination of the cerebrospinal fluid (CSF) revealed pleocytosis as well as elevated protein and interleukin (IL)-6 level...

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Bibliographic Details
Published in:Modern rheumatology 2006-10, Vol.16 (5), p.321-323
Main Authors: Hatachi, Saori, Nakazawa, Takashi, Morinobu, Akio, Kasagi, Shinpei, Kogata, Yoshinori, Kageyama, Gohichi, Kawano, Seiji, Koshiba, Masahiro, Kumagai, Shunichi
Format: Article
Language:English
Subjects:
Brain
Case studies
Medical diagnosis
Medical treatment
Neurological disorders
NMR
Nuclear magnetic resonance
Pediatrics
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Summary:Behcet's disease is rare in childhood. We describe a 10-year-old boy with neuro-Behcet's disease (NB) who presented with fever, headache, vertigo, and hearing loss. An examination of the cerebrospinal fluid (CSF) revealed pleocytosis as well as elevated protein and interleukin (IL)-6 levels. Brain magnetic resonance imaging (MRI) showed hyperintensity of the right thalamus and midbrain on T2-WI, and gadolinium (Gd) enhancement of left acoustic nerve origin. HLA-B51 was positive. Prednisolone combined with methotrexate resulted in a complete remission. Brain MRI and the CSF IL-6 level were useful for the diagnosis and monitoring of this pediatric patient with NB. [PUBLICATION ABSTRACT]
ISSN:1439-7595
1439-7609
DOI:10.1007/s10165-006-0507-1