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The particular relationship between Parkinson’s disease and malignancy: a focus on skin cancers
Although the risk for most cancers appears to be relatively low in patients with Parkinson’s disease (PD), skin cancers and melanomas occur more frequently in the PD population as compared to controls. This article summarizes the findings of cohort studies on skin cancer in Parkinson’s disease. Give...
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Published in: | Journal of Neural Transmission 2009-11, Vol.116 (11), p.1503-1507 |
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container_title | Journal of Neural Transmission |
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creator | Inzelberg, Rivka Israeli-Korn, Simon D. |
description | Although the risk for most cancers appears to be relatively low in patients with Parkinson’s disease (PD), skin cancers and melanomas occur more frequently in the PD population as compared to controls. This article summarizes the findings of cohort studies on skin cancer in Parkinson’s disease. Given that melanoma may precede use of
l
-dopa, the increased risk of melanoma for PD patients cannot be attributed to
l
-dopa. On the basis of these observations it may be reasonable to recommend that all patients with PD, whether treated with
l
-dopa or not, should undergo regular dermatological screening for neoplastic or pre-neoplastic skin lesions, especially melanoma. |
doi_str_mv | 10.1007/s00702-009-0322-x |
format | article |
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l
-dopa, the increased risk of melanoma for PD patients cannot be attributed to
l
-dopa. On the basis of these observations it may be reasonable to recommend that all patients with PD, whether treated with
l
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l
-dopa, the increased risk of melanoma for PD patients cannot be attributed to
l
-dopa. On the basis of these observations it may be reasonable to recommend that all patients with PD, whether treated with
l
-dopa or not, should undergo regular dermatological screening for neoplastic or pre-neoplastic skin lesions, especially melanoma.</description><subject>Antiparkinson Agents - adverse effects</subject><subject>Basic Neurosciences</subject><subject>Causality</subject><subject>Comorbidity</subject><subject>Genetics and Immunology - Review Article</subject><subject>Humans</subject><subject>Levodopa - adverse effects</subject><subject>Mass Screening</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Melanoma - epidemiology</subject><subject>Melanoma - etiology</subject><subject>Melanoma - physiopathology</subject><subject>Neurology</subject><subject>Neurosciences</subject><subject>Parkinson Disease - drug therapy</subject><subject>Parkinson Disease - epidemiology</subject><subject>Parkinson Disease - physiopathology</subject><subject>Psychiatry</subject><subject>Risk Factors</subject><subject>Skin Neoplasms - epidemiology</subject><subject>Skin Neoplasms - etiology</subject><subject>Skin Neoplasms - physiopathology</subject><issn>0300-9564</issn><issn>1435-1463</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><recordid>eNp1kM9KHEEQhxuJ6MbkAXIJTQ7eRqv_zM50bkFiIgjmYM5NbXeNjpnt2XTNEL35Gnk9nyQtuyAIuVRB9Ve_aj4hPig4UQDNKZcCugJwFRitq_s9sVDW1JWyS_NGLMAAVK5e2kPxlvkOAJRq2gNxqFzTuta4hcDrW5IbzFMf5gGzzDTg1I-Jb_uNXNH0hyjJH5h_9YnH9PT4l2XsmZBJYopyjUN_kzCFh88SZTeGmeWYJBdchjKmzO_EfocD0_tdPxI_z79en32vLq--XZx9uayCBTVVGpXVq8466JYtUO3ItKF2GHSnybU6xjo6a3TU0XauKdVECza2EG1ARHMkjre5mzz-noknv-450DBgonFmr5U21mlTwE-vwLtxzqn8rTBNa4pAKJDaQiGPzJk6v8n9GvODV-Cf5futfF_k-2f5_r7sfNwFz6s1xZeNne0C6C3A5SndUH65_P_Uf3nLkTw</recordid><startdate>20091101</startdate><enddate>20091101</enddate><creator>Inzelberg, Rivka</creator><creator>Israeli-Korn, Simon D.</creator><general>Springer Vienna</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7TK</scope></search><sort><creationdate>20091101</creationdate><title>The particular relationship between Parkinson’s disease and malignancy: a focus on skin cancers</title><author>Inzelberg, Rivka ; Israeli-Korn, Simon D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c401t-2a142bf490f680e59e38c59ac2f2e982dd5d9432d2d4f972d43d404d80d4caaa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Antiparkinson Agents - adverse effects</topic><topic>Basic Neurosciences</topic><topic>Causality</topic><topic>Comorbidity</topic><topic>Genetics and Immunology - Review Article</topic><topic>Humans</topic><topic>Levodopa - adverse effects</topic><topic>Mass Screening</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Melanoma - epidemiology</topic><topic>Melanoma - etiology</topic><topic>Melanoma - physiopathology</topic><topic>Neurology</topic><topic>Neurosciences</topic><topic>Parkinson Disease - drug therapy</topic><topic>Parkinson Disease - epidemiology</topic><topic>Parkinson Disease - physiopathology</topic><topic>Psychiatry</topic><topic>Risk Factors</topic><topic>Skin Neoplasms - epidemiology</topic><topic>Skin Neoplasms - etiology</topic><topic>Skin Neoplasms - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Inzelberg, Rivka</creatorcontrib><creatorcontrib>Israeli-Korn, Simon D.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Neurosciences Abstracts</collection><jtitle>Journal of Neural Transmission</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Inzelberg, Rivka</au><au>Israeli-Korn, Simon D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The particular relationship between Parkinson’s disease and malignancy: a focus on skin cancers</atitle><jtitle>Journal of Neural Transmission</jtitle><stitle>J Neural Transm</stitle><addtitle>J Neural Transm (Vienna)</addtitle><date>2009-11-01</date><risdate>2009</risdate><volume>116</volume><issue>11</issue><spage>1503</spage><epage>1507</epage><pages>1503-1507</pages><issn>0300-9564</issn><eissn>1435-1463</eissn><coden>JNTRF3</coden><abstract>Although the risk for most cancers appears to be relatively low in patients with Parkinson’s disease (PD), skin cancers and melanomas occur more frequently in the PD population as compared to controls. This article summarizes the findings of cohort studies on skin cancer in Parkinson’s disease. Given that melanoma may precede use of
l
-dopa, the increased risk of melanoma for PD patients cannot be attributed to
l
-dopa. On the basis of these observations it may be reasonable to recommend that all patients with PD, whether treated with
l
-dopa or not, should undergo regular dermatological screening for neoplastic or pre-neoplastic skin lesions, especially melanoma.</abstract><cop>Vienna</cop><pub>Springer Vienna</pub><pmid>19789839</pmid><doi>10.1007/s00702-009-0322-x</doi><tpages>5</tpages></addata></record> |
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subjects | Antiparkinson Agents - adverse effects Basic Neurosciences Causality Comorbidity Genetics and Immunology - Review Article Humans Levodopa - adverse effects Mass Screening Medicine Medicine & Public Health Melanoma - epidemiology Melanoma - etiology Melanoma - physiopathology Neurology Neurosciences Parkinson Disease - drug therapy Parkinson Disease - epidemiology Parkinson Disease - physiopathology Psychiatry Risk Factors Skin Neoplasms - epidemiology Skin Neoplasms - etiology Skin Neoplasms - physiopathology |
title | The particular relationship between Parkinson’s disease and malignancy: a focus on skin cancers |
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