Photodynamic therapy in vulvar lymphangioma: Case report

•A case report of rare vascular condition: Vulvar Lymphangioma.•Clinical response after 5 sessions of Methylene blue- mediated PDT.•Follow up - post 3 years no recurrence was observed.•PDT-MB for Vulvar Lymphangioma is a non-invasive, safety and low-cost treatment. •The aim of this case report was t...

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Bibliographic Details
Published in:Photodiagnosis and photodynamic therapy 2019-03, Vol.25, p.84-86
Main Authors: Belotto, Renata, Santos, Roberto Eusebio, Tardivo, João Paulo, Fernandes, Raquel, Baptista, Mauricio, Itri, Rosangela, Chavantes, Maria Cristina
Format: Article
Language:English
Subjects:
Female
Humans
Lymphangioma - drug therapy
Methylene blue
Methylene Blue - therapeutic use
Middle Aged
PDT
Photochemotherapy - methods
Photodynamic therapy
Photosensitizing Agents - therapeutic use
Vulvar disease
Vulvar lymphangioma
Vulvar Neoplasms - drug therapy
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Summary:•A case report of rare vascular condition: Vulvar Lymphangioma.•Clinical response after 5 sessions of Methylene blue- mediated PDT.•Follow up - post 3 years no recurrence was observed.•PDT-MB for Vulvar Lymphangioma is a non-invasive, safety and low-cost treatment. •The aim of this case report was to evaluate the treatment of vulvar lymphangioma applying photodynamic therapy (PDT). Patient aged 61 years, complained of vulvar region burning, local pain, which caused intense discomfort for over 5 years. She had developed vulvar edema, papules and vesicles that drained clear exudate, in which histological finding confirmed the vulvar lymphangioma. A red diode laser (Photon Lase III, DMC, Brazil) was applied locally after a 2% methylene blue aqueous solution (MB) in the vulvar target area. It was used a 660 nm wavelength light source, irradiance- 100 mW/cm2, radiant energy-20 J/cm2, exposer time-40 s, applied weekly at 10 points onto vulvar area in a total of 5 sessions. A clinical improvement post PDT was observed as well as a better quality of life. Post 3 years follow up no recurrence was observed. The clinical response followed MB- mediated PDT suggested a non-invasive, secure and low-cost treatment.
ISSN:1572-1000
1873-1597
DOI:10.1016/j.pdpdt.2018.09.001