Sleep disorders in primary antiphospholipid syndrome

The objective of this study was to evaluate the sleep quality, the presence of sleep disorders in patients with primary antiphospholipid syndrome (pAPS), and their possible clinical and laboratory associations. This was a cross-sectional study of 40 consecutive pAPS patients and 211 healthy age- and...

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Bibliographic Details
Published in:Clinical rheumatology 2018-12, Vol.37 (12), p.3345-3349
Main Authors: de Oliveira, Luana Viana, Sinicato, Nailú Angélica, Appenzeller, Simone, Rodrigues, Carlos Ewerton Maia, de Carvalho, Jozélio Freire
Format: Article
Language:English
Subjects:
Adolescent
Adult
Antibodies, Antiphospholipid - blood
Antiphospholipid antibodies
Antiphospholipid syndrome
Antiphospholipid Syndrome - complications
Autoimmune diseases
Brazil - epidemiology
Case-Control Studies
Cross-Sectional Studies
Female
Humans
Laboratories
Language
Male
Medicine
Medicine & Public Health
Middle Aged
Original Article
Quality
Retrospective Studies
Rheumatology
Sleep
Sleep deprivation
Sleep disorders
Sleep Wake Disorders - complications
Surveys and Questionnaires
Young Adult
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Summary:The objective of this study was to evaluate the sleep quality, the presence of sleep disorders in patients with primary antiphospholipid syndrome (pAPS), and their possible clinical and laboratory associations. This was a cross-sectional study of 40 consecutive pAPS patients and 211 healthy age- and sex-matched controls. Demographic and clinical data, drug use, and antiphospholipid antibodies were evaluated. Sleep was evaluated using the Pittsburgh Sleep Quality Index (PSQI). pAPS patients had significantly worse sleep quality than healthy controls. Analyzing the individual components, pAPS had worse scores in five of seven components: sleep duration ( p  = 0.002), habitual sleep efficiency ( p  = 0.003), sleep disturbance ( p  
ISSN:0770-3198
1434-9949
DOI:10.1007/s10067-018-4341-6