Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2016–2018)

One of the most cited limitations of capillary and microchip electrophoresis is the poor sensitivity. This review continues to update this series of biannual reviews, first published in Electrophoresis in 2007, on developments in the field of online/in‐line concentration methods in capillaries and m...

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Published in:Electrophoresis 2019-01, Vol.40 (1), p.17-39
Main Authors: Breadmore, Michael C, Grochocki, Wojciech, Kalsoom, Umme, Alves, Mónica N., Phung, Sui Ching, Rokh, Masoomeh Tehrani, Cabot, Joan M., Ghiasvand, Alireza, Li, Feng, Shallan, Aliaa I., Keyon, Aemi S. Abdul, Alhusban, Ala A., See, Hong Heng, Wuethrich, Alain, Dawod, Mohamed, Quirino, Joselito P
Format: Article
Language:English
Subjects:
Animals
Biomarkers - analysis
Capillaries
Cell Line
Chemical Fractionation
Electrochromatography
Electrophoresis
Electrophoresis, Capillary
Extraction
Focusing
Humans
Hydrogen-Ion Concentration
Isotachophoresis
Mice
Micelles
Preconcentration
Sampling methods
Semiconductors
Sensitivity and Specificity
Sensitivity enhancement
Stacking
Sweeping
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Summary:One of the most cited limitations of capillary and microchip electrophoresis is the poor sensitivity. This review continues to update this series of biannual reviews, first published in Electrophoresis in 2007, on developments in the field of online/in‐line concentration methods in capillaries and microchips, covering the period July 2016–June 2018. It includes developments in the field of stacking, covering all methods from field‐amplified sample stacking and large‐volume sample stacking, through to isotachophoresis, dynamic pH junction, and sweeping. Attention is also given to online or in‐line extraction methods that have been used for electrophoresis.
ISSN:0173-0835
1522-2683
DOI:10.1002/elps.201800384