Bioactive constituents obtained from the fruits of Citrus aurantium

Three new compounds, citrusauranosides A ( 1 ), B ( 2 ), and C ( 3 ), along with 22 known compounds ( 4 – 25 ) were obtained from the 70% ethanol–water extract of the fruits of Citrus aurantium L.. Their structures were identified by spectroscopic methods. Among the known compounds, 14 , 15 , 17 and...

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Bibliographic Details
Published in:Journal of natural medicines 2019-01, Vol.73 (1), p.146-153
Main Authors: Zhang, Yi, Huang, Peijian, He, Wei, Sakah, Kaunda Joseph, Ruan, Jingya, Li, Zheng, Wang, Tao
Format: Article
Language:English
Subjects:
Animals
Biomedical and Life Sciences
Biomedicine
Citrus - chemistry
Citrus fruits
Complementary & Alternative Medicine
Digestive system
Fruit - chemistry
Humans
Male
Medicinal Chemistry
Mice
Organic chemicals
Original Paper
Pharmacology/Toxicology
Pharmacy
Phytochemicals
Plant Extracts - chemistry
Plant Sciences
Rodents
Trees
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Summary:Three new compounds, citrusauranosides A ( 1 ), B ( 2 ), and C ( 3 ), along with 22 known compounds ( 4 – 25 ) were obtained from the 70% ethanol–water extract of the fruits of Citrus aurantium L.. Their structures were identified by spectroscopic methods. Among the known compounds, 14 , 15 , 17 and 23 were firstly obtained from Citrus genus, and the NMR data of 17 is reported here for the first time. Moreover, inhibitory effects of all compounds on motility of mouse isolated intestine tissue were determined. As a result, 1 , 4 – 8 , and 11 displayed significant inhibitory effects on contraction tension.
ISSN:1340-3443
1861-0293
DOI:10.1007/s11418-018-1255-1