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Bioactive constituents obtained from the fruits of Citrus aurantium
Three new compounds, citrusauranosides A ( 1 ), B ( 2 ), and C ( 3 ), along with 22 known compounds ( 4 – 25 ) were obtained from the 70% ethanol–water extract of the fruits of Citrus aurantium L.. Their structures were identified by spectroscopic methods. Among the known compounds, 14 , 15 , 17 and...
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| Published in: | Journal of natural medicines 2019-01, Vol.73 (1), p.146-153 |
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| Main Authors: | , , , , , , |
| Format: | Article |
| Language: | English |
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| cites | cdi_FETCH-LOGICAL-c489t-b9a7901d813d6ed7b6689b8405db6b74d8d1c1a88fc75c69c54597a85e93d90c3 |
| container_end_page | 153 |
| container_issue | 1 |
| container_start_page | 146 |
| container_title | Journal of natural medicines |
| container_volume | 73 |
| creator | Zhang, Yi Huang, Peijian He, Wei Sakah, Kaunda Joseph Ruan, Jingya Li, Zheng Wang, Tao |
| description | Three new compounds, citrusauranosides A (
1
), B (
2
), and C (
3
), along with 22 known compounds (
4
–
25
) were obtained from the 70% ethanol–water extract of the fruits of
Citrus aurantium
L.. Their structures were identified by spectroscopic methods. Among the known compounds,
14
,
15
,
17
and
23
were firstly obtained from
Citrus
genus, and the NMR data of
17
is reported here for the first time. Moreover, inhibitory effects of all compounds on motility of mouse isolated intestine tissue were determined. As a result,
1
,
4
–
8
, and
11
displayed significant inhibitory effects on contraction tension. |
| doi_str_mv | 10.1007/s11418-018-1255-1 |
| format | article |
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1
), B (
2
), and C (
3
), along with 22 known compounds (
4
–
25
) were obtained from the 70% ethanol–water extract of the fruits of
Citrus aurantium
L.. Their structures were identified by spectroscopic methods. Among the known compounds,
14
,
15
,
17
and
23
were firstly obtained from
Citrus
genus, and the NMR data of
17
is reported here for the first time. Moreover, inhibitory effects of all compounds on motility of mouse isolated intestine tissue were determined. As a result,
1
,
4
–
8
, and
11
displayed significant inhibitory effects on contraction tension.</description><identifier>ISSN: 1340-3443</identifier><identifier>EISSN: 1861-0293</identifier><identifier>DOI: 10.1007/s11418-018-1255-1</identifier><identifier>PMID: 30367360</identifier><language>eng</language><publisher>Singapore: Springer Singapore</publisher><subject>Animals ; Biomedical and Life Sciences ; Biomedicine ; Citrus - chemistry ; Citrus fruits ; Complementary & Alternative Medicine ; Digestive system ; Fruit - chemistry ; Humans ; Male ; Medicinal Chemistry ; Mice ; Organic chemicals ; Original Paper ; Pharmacology/Toxicology ; Pharmacy ; Phytochemicals ; Plant Extracts - chemistry ; Plant Sciences ; Rodents ; Trees</subject><ispartof>Journal of natural medicines, 2019-01, Vol.73 (1), p.146-153</ispartof><rights>The Japanese Society of Pharmacognosy and Springer Japan KK, part of Springer Nature 2018</rights><rights>The Japanese Society of Pharmacognosy and Springer Japan KK, part of Springer Nature 2018.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c489t-b9a7901d813d6ed7b6689b8405db6b74d8d1c1a88fc75c69c54597a85e93d90c3</citedby><cites>FETCH-LOGICAL-c489t-b9a7901d813d6ed7b6689b8405db6b74d8d1c1a88fc75c69c54597a85e93d90c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30367360$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhang, Yi</creatorcontrib><creatorcontrib>Huang, Peijian</creatorcontrib><creatorcontrib>He, Wei</creatorcontrib><creatorcontrib>Sakah, Kaunda Joseph</creatorcontrib><creatorcontrib>Ruan, Jingya</creatorcontrib><creatorcontrib>Li, Zheng</creatorcontrib><creatorcontrib>Wang, Tao</creatorcontrib><title>Bioactive constituents obtained from the fruits of Citrus aurantium</title><title>Journal of natural medicines</title><addtitle>J Nat Med</addtitle><addtitle>J Nat Med</addtitle><description>Three new compounds, citrusauranosides A (
1
), B (
2
), and C (
3
), along with 22 known compounds (
4
–
25
) were obtained from the 70% ethanol–water extract of the fruits of
Citrus aurantium
L.. Their structures were identified by spectroscopic methods. Among the known compounds,
14
,
15
,
17
and
23
were firstly obtained from
Citrus
genus, and the NMR data of
17
is reported here for the first time. Moreover, inhibitory effects of all compounds on motility of mouse isolated intestine tissue were determined. As a result,
1
,
4
–
8
, and
11
displayed significant inhibitory effects on contraction tension.</description><subject>Animals</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Citrus - chemistry</subject><subject>Citrus fruits</subject><subject>Complementary & Alternative Medicine</subject><subject>Digestive system</subject><subject>Fruit - chemistry</subject><subject>Humans</subject><subject>Male</subject><subject>Medicinal Chemistry</subject><subject>Mice</subject><subject>Organic chemicals</subject><subject>Original Paper</subject><subject>Pharmacology/Toxicology</subject><subject>Pharmacy</subject><subject>Phytochemicals</subject><subject>Plant Extracts - chemistry</subject><subject>Plant Sciences</subject><subject>Rodents</subject><subject>Trees</subject><issn>1340-3443</issn><issn>1861-0293</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNp1kE1rGzEQhkVpqR0nPyCXsNBLL9toVt_HxqRJwZBLchZaSZvIeHddfRT67yNjN4FCD2IG5tE7w4PQJeBvgLG4TgAUZIvrg46xFj6gJUgOLe4U-Vh7QnFLKCULdJbSFmPaEQKf0YJgwgXheInWN2E2NoffvrHzlHLIxU85NXOfTZi8a4Y4j01-8bUp4TAYmnXIsaTGlGimHMp4jj4NZpf8xamu0NOP28f1fbt5uPu5_r5pLZUqt70yQmFwEojj3omec6l6STFzPe8FddKBBSPlYAWzXFlGmRJGMq-IU9iSFfp6zN3H-VfxKesxJOt3OzP5uSTdQccVCKWgol_-QbdziVO9rlKcAWUdiErBkbJxTin6Qe9jGE38owHrg2F9NKyrYX0wrA_JV6fk0o_evf34q7QC3RFIdTQ9-_i--v-prwPJhSM</recordid><startdate>20190101</startdate><enddate>20190101</enddate><creator>Zhang, Yi</creator><creator>Huang, Peijian</creator><creator>He, Wei</creator><creator>Sakah, Kaunda Joseph</creator><creator>Ruan, Jingya</creator><creator>Li, Zheng</creator><creator>Wang, Tao</creator><general>Springer Singapore</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>20190101</creationdate><title>Bioactive constituents obtained from the fruits of Citrus aurantium</title><author>Zhang, Yi ; Huang, Peijian ; He, Wei ; Sakah, Kaunda Joseph ; Ruan, Jingya ; Li, Zheng ; Wang, Tao</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c489t-b9a7901d813d6ed7b6689b8405db6b74d8d1c1a88fc75c69c54597a85e93d90c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Animals</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Citrus - chemistry</topic><topic>Citrus fruits</topic><topic>Complementary & Alternative Medicine</topic><topic>Digestive system</topic><topic>Fruit - chemistry</topic><topic>Humans</topic><topic>Male</topic><topic>Medicinal Chemistry</topic><topic>Mice</topic><topic>Organic chemicals</topic><topic>Original Paper</topic><topic>Pharmacology/Toxicology</topic><topic>Pharmacy</topic><topic>Phytochemicals</topic><topic>Plant Extracts - chemistry</topic><topic>Plant Sciences</topic><topic>Rodents</topic><topic>Trees</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Yi</creatorcontrib><creatorcontrib>Huang, Peijian</creatorcontrib><creatorcontrib>He, Wei</creatorcontrib><creatorcontrib>Sakah, Kaunda Joseph</creatorcontrib><creatorcontrib>Ruan, Jingya</creatorcontrib><creatorcontrib>Li, Zheng</creatorcontrib><creatorcontrib>Wang, Tao</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of natural medicines</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Yi</au><au>Huang, Peijian</au><au>He, Wei</au><au>Sakah, Kaunda Joseph</au><au>Ruan, Jingya</au><au>Li, Zheng</au><au>Wang, Tao</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bioactive constituents obtained from the fruits of Citrus aurantium</atitle><jtitle>Journal of natural medicines</jtitle><stitle>J Nat Med</stitle><addtitle>J Nat Med</addtitle><date>2019-01-01</date><risdate>2019</risdate><volume>73</volume><issue>1</issue><spage>146</spage><epage>153</epage><pages>146-153</pages><issn>1340-3443</issn><eissn>1861-0293</eissn><abstract>Three new compounds, citrusauranosides A (
1
), B (
2
), and C (
3
), along with 22 known compounds (
4
–
25
) were obtained from the 70% ethanol–water extract of the fruits of
Citrus aurantium
L.. Their structures were identified by spectroscopic methods. Among the known compounds,
14
,
15
,
17
and
23
were firstly obtained from
Citrus
genus, and the NMR data of
17
is reported here for the first time. Moreover, inhibitory effects of all compounds on motility of mouse isolated intestine tissue were determined. As a result,
1
,
4
–
8
, and
11
displayed significant inhibitory effects on contraction tension.</abstract><cop>Singapore</cop><pub>Springer Singapore</pub><pmid>30367360</pmid><doi>10.1007/s11418-018-1255-1</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1340-3443 |
| ispartof | Journal of natural medicines, 2019-01, Vol.73 (1), p.146-153 |
| issn | 1340-3443 1861-0293 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2126917991 |
| source | Springer Nature |
| subjects | Animals Biomedical and Life Sciences Biomedicine Citrus - chemistry Citrus fruits Complementary & Alternative Medicine Digestive system Fruit - chemistry Humans Male Medicinal Chemistry Mice Organic chemicals Original Paper Pharmacology/Toxicology Pharmacy Phytochemicals Plant Extracts - chemistry Plant Sciences Rodents Trees |
| title | Bioactive constituents obtained from the fruits of Citrus aurantium |
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