Palladium-catalyzed olefination of aryl/alkyl halides with trimethylsilyldiazomethane via carbene migratory insertion

The direct olefination of aryl/alkyl halides with trimethylsilyldiazomethane (TMSD) as a C1- or C2-unit was achieved successfully via a metal carbene migratory insertion process, which offered a new access to afford (E)-vinyl silanes and (E)-silyl-substituted α,β-unsaturated amides in good yields an...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2018-11, Vol.54 (92), p.12994-12997
Main Authors: Mu, Qiu-Chao, Wang, Xing-Ben, Ye, Fei, Sun, Yu-Li, Bai, Xing-Feng, Chen, Jing, Xia, Chun-Gu, Xu, Li-Wen
Format: Article
Language:English
Subjects:
Amides
Aromatic compounds
Halides
Insertion
Palladium
Silanes
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Summary:The direct olefination of aryl/alkyl halides with trimethylsilyldiazomethane (TMSD) as a C1- or C2-unit was achieved successfully via a metal carbene migratory insertion process, which offered a new access to afford (E)-vinyl silanes and (E)-silyl-substituted α,β-unsaturated amides in good yields and high chemoselectivity.
ISSN:1359-7345
1364-548X
DOI:10.1039/C8CC07664B