Salvage Lymph Node Dissection for Nodal Recurrent Prostate Cancer: A Systematic Review

Identification of early nodal recurrence after primary prostate cancer (PCa) treatment by functional imaging may guide metastasis-directed therapy such as salvage lymph node dissection (SLND). The aim of this systematic review was to assess the oncological role and the safety of SLND in the era of m...

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Bibliographic Details
Published in:European urology 2019-10, Vol.76 (4), p.493-504
Main Authors: Ploussard, Guillaume, Gandaglia, Giorgio, Borgmann, Hendrik, de Visschere, Pieter, Heidegger, Isabel, Kretschmer, Alexander, Mathieu, Romain, Surcel, Cristian, Tilki, Derya, Tsaur, Igor, Valerio, Massimo, van den Bergh, Roderick, Ost, Piet, Briganti, Alberto
Format: Article
Language:English
Subjects:
Lymph node dissection
Nodal recurrence
Prostate cancer
Recurrence
Salvage treatment
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Summary:Identification of early nodal recurrence after primary prostate cancer (PCa) treatment by functional imaging may guide metastasis-directed therapy such as salvage lymph node dissection (SLND). The aim of this systematic review was to assess the oncological role and the safety of SLND in the era of modern imaging in case of exclusive nodal recurrence after primary PCa treatment with curative intent. A systematic literature search in the PubMed and Cochrane databases was performed up to August 2018 according to Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines. Overall, 27 SLND series have been selected for synthesis. Prostate-specific membrane antigen or choline positron emission tomography/computed tomography was the reference detection technique. SLND was performed by open or laparoscopic approach with
ISSN:0302-2838
1873-7560
DOI:10.1016/j.eururo.2018.10.041