Detection of Pediatric Pulmonary Arterial Hypertension by School Electrocardiography Mass Screening

To detect pulmonary arterial hypertension (PAH) at any early stage is a promising approach to optimize the outcome. To investigate the impact of school ECG-based screening on detecting idiopathic or heritable (I/H)-PAH in the general pediatric population. This was a nationwide survey of patients wit...

Full description

Saved in:
Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2019-06, Vol.199 (11), p.1397-1406
Main Authors: Sawada, Hirofumi, Mitani, Yoshihide, Nakayama, Tomotaka, Fukushima, Hiroyuki, Kogaki, Shigetoyo, Igarashi, Takehiro, Ichida, Fukiko, Ono, Yasuo, Nakanishi, Toshio, Doi, Shozaburo, Ishikawa, Shiro, Matsushima, Masaki, Yamada, Osamu, Saji, Tsutomu
Format: Article
Language:English
Subjects:
Achievement tests
Adolescent
Age
Cardiology
Cardiovascular disease
Child
Child, Preschool
Committees
Councils
Early Diagnosis
Electrocardiography
Electrocardiography - methods
Epidemiology
Familial Primary Pulmonary Hypertension - diagnosis
Female
Genomics
Heart surgery
Hemodynamics
Hospitals
Humans
Infant
Japan
Male
Mass Screening - methods
Mass Screening - statistics & numerical data
Medical prognosis
Medicine
Pediatrics
Population
Pulmonary arteries
Pulmonary hypertension
Retrospective Studies
School Health Services - statistics & numerical data
Schools
Society
Students
Veins & arteries
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To detect pulmonary arterial hypertension (PAH) at any early stage is a promising approach to optimize the outcome. To investigate the impact of school ECG-based screening on detecting idiopathic or heritable (I/H)-PAH in the general pediatric population. This was a nationwide survey of patients with I/H-PAH newly diagnosed at 3 months to 18 years of age in Japan during 2005-2012. Eighty-seven eligible patients (age range, 1-16 yr) were recruited. Among 68 (78%) patients diagnosed at greater than or equal to 6 years of age (the age of the first ECG-based screening), 28 (41%) were detected by the ECG-based screening (screening group) and 40 (59%) were recognized by their symptoms (  = 37) or coincidental occasions (  = 3; nonscreening group). In the screening group, the proportion of patients in World Health Organization functional class I/II at diagnosis was higher (96% vs. 60%;  
ISSN:1073-449X
1535-4970
DOI:10.1164/rccm.201802-0375oc