Debio 025, a Cyclophilin Binding Molecule, Is Highly Efficient in Clearing Hepatitis C Virus (HCV) Replicon-Containing Cells When Used Alone or in Combination with Specifically Targeted Antiviral Therapy for HCV (STAT-C) Inhibitors

• Published in: Antimicrobial Agents and Chemotherapy 2009-03, Vol.53 (3), p.967-976
• Main Authors: Coelmont, Lotte, Kaptein, Suzanne, Paeshuyse, Jan, Vliegen, Inge, Dumont, Jean-Maurice, Vuagniaux, Grégoire, Neyts, Johan
• Format: Article
• Language: English
• Subjects: Antiviral Agents; Antiviral Agents - pharmacology; Clinical Trials as Topic; Cyclophilins - metabolism; Cyclosporine; Cyclosporine - pharmacology; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Hepacivirus; Hepacivirus - drug effects; Hepacivirus - genetics; Hepacivirus - metabolism; Hepatitis C; Hepatitis C - drug therapy; Hepatitis C - genetics; Hepatitis C virus; Humans; Replicon - drug effects; Ribavirin - pharmacology; Viral Nonstructural Proteins; Viral Nonstructural Proteins - antagonists & inhibitors; Viral Nonstructural Proteins - genetics
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.00939-08

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