Pediatric Quality of Life Inventory (PedsQL) 3.2 Diabetes Module for youth with Type 2 diabetes: reliability and validity

• Published in: Diabetic medicine 2019-04, Vol.36 (4), p.465-472
• Main Authors: Varni, J. W., Delamater, A. M., Hood, K. K., Raymond, J. K., Chang, N. T., Driscoll, K. A., Wong, J. C., Yi‐Frazier, J. P., Grishman, E. K., Faith, M. A., Corathers, S. D., Kichler, J. C., Miller, J. L., Doskey, E. M., Aguirre, V. P., Heffer, R. W., Wilson, D. P.
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Age Factors; Age of Onset; Child; Diabetes; Diabetes mellitus; Diabetes mellitus (insulin dependent); Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 1 - diagnosis; Diabetes Mellitus, Type 1 - psychology; Diabetes Mellitus, Type 2 - diagnosis; Diabetes Mellitus, Type 2 - epidemiology; Diabetes Mellitus, Type 2 - psychology; Disease management; Factor analysis; Feasibility Studies; Female; Glucose; Health Status; Humans; Male; Patient Reported Outcome Measures; Pediatrics; Psychometrics - methods; Quality of Life; Reproducibility of Results; Surveys and Questionnaires - standards; Young Adult
• ISSN: 0742-3071; 1464-5491
• DOI: 10.1111/dme.13841

Aim To test the measurement properties of the revised and updated Pediatric Quality of Life Inventory (PedsQL) 3.2 Diabetes Module originally developed in Type 1 diabetes in youth with Type 2 diabetes. Methods The PedsQL 3.2 Diabetes Module and PedsQL Generic Core Scales were administered in a field test study to 100 young people aged 9–25 years with Type 2 diabetes. Factor analysis was conducted to determine the factor structure of the items. Results The 15‐item Diabetes Symptoms Summary Score and 12‐item Type 2‐specific Diabetes Management Summary Score were empirically derived through factor analysis. The Diabetes Symptoms and Type 2‐specific Diabetes Management Summary Scores showed acceptable to excellent reliability across the age groups tested (α = 0.85–0.94). The Diabetes Symptoms and Type 2‐specific Diabetes Management Summary Scores evidenced construct validity through large effect size correlations with the Generic Core Scales Total Scale Score (r = 0.67 and 0.57, respectively). HbA1c was correlated with the Diabetes Symptoms and Type 2‐specific Diabetes Management Summary Scores (r = −0.13 and −0.22). Minimal clinically important difference (MCID) scores were 5.91 and 7.39 for the Diabetes Symptoms and Type 2‐specific Diabetes Management Summary Scores. Conclusions The PedsQL 3.2 Diabetes Module Diabetes Symptoms Summary Score and Type 2‐specific Diabetes Management Summary Score exhibited satisfactory measurement properties for use as youth self‐reported diabetes symptoms and diabetes management outcomes for clinical research and clinical practice for young people with Type 2 diabetes. What's new? Worldwide incidence and prevalence of Type 2 diabetes in youth have increased dramatically. Systematic measurement of young people's perceptions of the impact of Type 2 diabetes on their health‐related quality of life represents an essential component of comprehensive care. The new PedsQL 3.2 Diabetes Module measurement properties in young people with Type 2 diabetes have not been previously reported. Findings support the feasibility, internal consistency reliability, construct validity and minimal clinically important difference of the PedsQL 3.2 Diabetes Module Diabetes Symptoms and Type 2‐specific Diabetes Management Summary Scores for young people with Type 2 diabetes.