Gender differences in homocysteine concentrations, a population-based cross-sectional study

High concentrations of homocysteine are considered a risk factor for atherosclerosis and coronary artery disease. The aim of this study was to assess whether or not there are gender differences in the plasma concentrations of homocysteine. Data were collected from medical records of individuals exam...

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Published in:Nutrition, metabolism, and cardiovascular diseases metabolism, and cardiovascular diseases, 2019-01, Vol.29 (1), p.9-14
Main Authors: Cohen, E., Margalit, I., Shochat, T., Goldberg, E., Krause, I.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Atherosclerosis - blood
Atherosclerosis - epidemiology
Biomarkers - blood
Coronary artery disease
Coronary Artery Disease - blood
Coronary Artery Disease - epidemiology
Cross-Sectional Studies
Female
Folate
Folic Acid Deficiency - blood
Folic Acid Deficiency - epidemiology
Gender
Homocysteine
Homocysteine - blood
Humans
Hyperhomocysteinemia - blood
Hyperhomocysteinemia - diagnosis
Hyperhomocysteinemia - epidemiology
Israel
Male
Middle Aged
Prevalence
Prognosis
Risk Factors
Sex Factors
Vitamin B 12 Deficiency - blood
Vitamin B 12 Deficiency - epidemiology
Vitamin B12
Young Adult
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Summary:High concentrations of homocysteine are considered a risk factor for atherosclerosis and coronary artery disease. The aim of this study was to assess whether or not there are gender differences in the plasma concentrations of homocysteine. Data were collected from medical records of individuals examined at a screening center in Israel between the years 2000–2014. Cross sectional analysis was carried out on 9237 men and 4353 women. Mean (SD) age of the study sample was 48.4 (9.7) and 47.7 (9.7) years for men and women respectively. Average homocysteine concentrations were 12.6 (5.9) and 9.6 (3.2) μmol/L in men and women respectively (p 
ISSN:0939-4753
1590-3729
DOI:10.1016/j.numecd.2018.09.003