Compatibility between a rabies vaccine and a combined vaccine against canine distemper, adenovirosis, parvovirosis, parainfluenza virus and leptospirosis

In many cicumstances, veterinarians are requiring to be able to administer rabies vaccine in dogs at the same time as vaccinating against canine distemper, adenovirus, parvovirus, parainfluenza virus and leptospirosis. The aim of this study was to assess the compatibility between a multivalent vacci...

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Bibliographic Details
Published in:Veterinary immunology and immunopathology 2018-11, Vol.205, p.93-96
Main Authors: Bouvet, J., Cariou, C., Poulard, A., Oberli, F., Cupillard, L., Guigal, P.M.
Format: Article
Language:English
Subjects:
Adenoviridae Infections - prevention & control
Adenoviridae Infections - veterinary
Animals
Antibodies, Neutralizing - immunology
Bacterial Vaccines - immunology
Compatibility
DAPPi-L
Distemper - prevention & control
Dog
Dog Diseases - prevention & control
Dog Diseases - virology
Dogs
Female
Immunization Schedule
Leptospirosis - prevention & control
Leptospirosis - veterinary
Male
Parvoviridae Infections - prevention & control
Parvoviridae Infections - veterinary
Rabies
Rabies - prevention & control
Rabies - veterinary
Rabies Vaccines - immunology
Respirovirus Infections - prevention & control
Respirovirus Infections - veterinary
Seroconversion
Vaccination - veterinary
Vaccine
Vaccines, Attenuated - immunology
Vaccines, Combined - immunology
Viral Vaccines - immunology
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Summary:In many cicumstances, veterinarians are requiring to be able to administer rabies vaccine in dogs at the same time as vaccinating against canine distemper, adenovirus, parvovirus, parainfluenza virus and leptospirosis. The aim of this study was to assess the compatibility between a multivalent vaccine and a rabies vaccine when injected at two separate sites. Lack of interference was assessed by comparing serological response to viral components during one year following primary vaccination with vaccines administered alone or concomitantly. Antibody response to all tested components was comparable, irrespective of whether vaccines were administered individually or concurrently. Notably, the rabies vaccine induced very strong and protective seroconversion in dogs, whether it was administered concomitantly with the combo vaccine or not. This facilitates administration of rabies vaccine, which is a key factor for controlling the disease.
ISSN:0165-2427
1873-2534
DOI:10.1016/j.vetimm.2018.11.001