Laser surface modification of polymers to improve biocompatibility: HEMA grafted PDMS, in vitro assay—III

Polydimethylsiloxane (PDMS) surface modifications were carried out using CO2-pulsed laser, without photosensitizer at ambient condition, to introduce peroxide groups onto the PDMS surface. Such peroxides were capable of initiating graft polymerization of 2-hydroxyethyl methacrylate (HEMA) onto the P...

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Bibliographic Details
Published in:Radiation physics and chemistry (1993) 1999-08, Vol.55 (5-6), p.685-689
Main Authors: Khorasani, M.T, Mirzadeh, H, Sammes, P.G
Format: Article
Language:English
Subjects:
Applied sciences
Biocompatibility
Exact sciences and technology
Grafting and modifications
Physicochemistry of polymers
Polymerization
Polymers
Polymers and radiations
Pulsed laser applications
Scanning electron microscopy
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Summary:Polydimethylsiloxane (PDMS) surface modifications were carried out using CO2-pulsed laser, without photosensitizer at ambient condition, to introduce peroxide groups onto the PDMS surface. Such peroxides were capable of initiating graft polymerization of 2-hydroxyethyl methacrylate (HEMA) onto the PDMS. The modified surfaces were characterized using a variety of techniques including scanning electron microscopy (SEM), attenuated total reflectance infrared (ATR-FTIR) and the water drop contact angle measurements. Data from in vitro assays indicated a significant reduction of the platelet adhesion and aggregation for the modified surfaces.
ISSN:0969-806X
1879-0895
DOI:10.1016/S0969-806X(99)00212-1