Relative contributions of individual deposition mechanisms to total aerosol deposition in human airways

The present study analyzed the aerosol particle deposition patterns, produced by the separate as well as the simultaneous action of deposition mechanisms (inertial impaction, gravitational settling, Brownian motion, and interception) in characteristic regions of the human airway system as a function...

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Bibliographic Details
Published in:Journal of aerosol science 1999-09, Vol.30 (Suppl. 1), p.S729-S730
Main Authors: Balásházy, I., Hofmann, W., Lo˝rinc, M.
Format: Article
Language:English
Subjects:
Bifurcation (mathematics)
Brownian movement
Density (specific gravity)
Diffusion in gases
Flow of fluids
Gravitational effects
Particle size analysis
Respiratory mechanics
Risk assessment
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Summary:The present study analyzed the aerosol particle deposition patterns, produced by the separate as well as the simultaneous action of deposition mechanisms (inertial impaction, gravitational settling, Brownian motion, and interception) in characteristic regions of the human airway system as a function of particle size and flow rate. The ratio of local to average deposition densities (enhancement factors) was computed by scanning along th whole surface of the bifurcation with a prespecified surface area element. Results showed that, in general, all deposition patterns caused by any deposition mechanisms are inhomogeneous in human airway bifurcations, both in the upper and lower regions of the human lung. This inhomogeneity usually increases with particle size and flow rate, and decreases with deeper penetration into the respiratory tract.
ISSN:0021-8502
1879-1964
DOI:10.1016/S0021-8502(99)80375-9