Enzymatic acylation of cellulose acetate in organic media

Cellulose fatty esters were prepared by acylation of cellulose acetate with various fatty acids catalyzed by immobilized lipase from Candida antarctica (Novozyme) in acetonitrile. The reaction parameters affecting the biocatalytic process such as the role of the nature of the substrates, the concent...

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Bibliographic Details
Published in:Journal of biotechnology 1998-12, Vol.66 (2), p.219-223
Main Authors: Sereti, V, Stamatis, H, Koukios, E, Kolisis, F.N
Format: Article
Language:English
Subjects:
Acetonitrile
Acylation
Bioconversions. Hemisynthesis
Biological and medical sciences
Biotechnology
Candida antarctica
Catalysis
Cellulose acetate
Chemical bonds
Enzyme immobilization
Esterification
Esters
Fatty acids
Fundamental and applied biological sciences. Psychology
Lipases
Methods. Procedures. Technologies
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Summary:Cellulose fatty esters were prepared by acylation of cellulose acetate with various fatty acids catalyzed by immobilized lipase from Candida antarctica (Novozyme) in acetonitrile. The reaction parameters affecting the biocatalytic process such as the role of the nature of the substrates, the concentration of the enzyme and the reactants as well as the agitation speed of the reaction mixture have been investigated. At optimum reaction conditions about 35% of the initial amount of fatty acid were incorporated on the modified cellulose acetate molecule, while an increase of 2% of the ester bonds was observed on the final product.
ISSN:0168-1656
1873-4863
DOI:10.1016/S0168-1656(98)00085-6