The combined effect of serum cystatin C and dyslipidemia on hypertension in a large health check-up population in China

OBJECTIVE: Some studies have reported that both serum cystatin C (Cys C) and dyslipidemia are independently associated with hypertension. However, the combined effect of the two factors is still unknown. The present study was aimed at investigating the effect of Cys C combined with dyslipidemia on h...

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Published in:Clinical and experimental hypertension (1993) 2019-11, Vol.41 (8), p.702-707
Main Authors: Ma, Jun, Wu, Zewei, Zha, Xiaojuan, Zhu, Xinying, Li, Wenbo, Jiang, Mingfei, Wang, Shuyi, Wu, Shouzhi, Wen, Yufeng
Format: Article
Language:English
Subjects:
combined effect
dyslipidemia
Hypertension
large samples
serum cystatin C
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Summary:OBJECTIVE: Some studies have reported that both serum cystatin C (Cys C) and dyslipidemia are independently associated with hypertension. However, the combined effect of the two factors is still unknown. The present study was aimed at investigating the effect of Cys C combined with dyslipidemia on hypertension in a large health check-up population in China. METHODS: A total of 203 233 health check-up subjects from January 2011 to July 2016 were recruited into this cross-sectional study. A multivariate logistic regression model was used to evaluate the combined effect of Cys C and dyslipidemia on hypertension. RESULTS: In univariate analysis, Cys C, high-density lipoprotein cholesterol, low-density lipoprotein, total cholesterol, and triglycerides were independently correlated with hypertension (p 
ISSN:1064-1963
1525-6006
DOI:10.1080/10641963.2018.1545845