Microbial β- N-acetylhexosaminidases and their biotechnological applications

Oligosaccharides containing a β- N-acetylglucosamine moiety are useful building blocks for the synthesis of complex substances with important functions in vivo, such as cell recognition, adhesion, and communication. Microbial β- N-acetylhexosaminidases have been applied to the preparation of a wide...

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Bibliographic Details
Published in:Enzyme and Microbial Technology 1999-07, Vol.25 (1), p.3-14
Main Authors: Scigelova, Michaela, Crout, David H.G.
Format: Article
Language:English
Subjects:
Amino acids
Applications
Biological and medical sciences
Biology of microorganisms of confirmed or potential industrial interest
Biotechnology
Catalysis
Chitobiase
Fundamental and applied biological sciences. Psychology
Fungi
Microbial β- N-acetylhexosaminidase
Miscellaneous
Mission oriented research
Polysaccharides
Sequence
Synthesis (chemical)
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Summary:Oligosaccharides containing a β- N-acetylglucosamine moiety are useful building blocks for the synthesis of complex substances with important functions in vivo, such as cell recognition, adhesion, and communication. Microbial β- N-acetylhexosaminidases have been applied to the preparation of a wide range of such biologically significant compounds. In addition, they have been employed for the analysis of complex sugar chains in glycoproteins and glycopeptides, and they have found application as biocontrol agents, particularly against fungal pathogens of plants. This survey compares amino acid sequence data, biochemical characteristics, and catalytic properties of β- N-acetylhexosaminidases from a number of microbial sources.
ISSN:0141-0229
1879-0909
DOI:10.1016/S0141-0229(98)00171-9