Quantifiable adhesion assay using a spinning disk device to measure the adherent strength of BCR/ABL transformed cells to a fibronectin matrix

Chronic myelogenous leukemia (CML) is a myeloproliferative disorder precipitated by the formation of bcr/abl chromosomal translocation. A novel method for studying adhesion in cell lines transformed by bcr/abl is presented.

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Bibliographic Details
Published in:Annals of biomedical engineering 2000-01, Vol.28 (SUPPL. 1), p.S-84
Main Authors: Wertheim, Jason, Hammer, Daniel, Boettiger, David, Pear, Warren
Format: Article
Language:English
Subjects:
Bioassay
Biomechanics
Biomedical engineering
Biomedical equipment
Cytology
Shear flow
Online Access:Get full text
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Description
Summary:Chronic myelogenous leukemia (CML) is a myeloproliferative disorder precipitated by the formation of bcr/abl chromosomal translocation. A novel method for studying adhesion in cell lines transformed by bcr/abl is presented.
ISSN:0090-6964