Biologically Programmed Nanoparticle Assembly

The use of protein–substrate binding to program the self‐assembly of nanoparticle‐based structures from aqueous solution is highlighted here. The systems discussed include aqueous dispersions of metal nanoparticles with surface‐attached antibodies and bivalent antigens in solution (see Figure), and...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2000-01, Vol.12 (2), p.147-150
Main Authors: Mann, S., Shenton, W., Li, M., Connolly, S., Fitzmaurice, D.
Format: Article
Language:English
Subjects:
Agglomeration
Antibodies
Antigens
Molecular recognition
Nanoparticle assembly
Nanostructured materials
Oxides
Particles (particulate matter)
Proteins
Self-assembly
Solutions
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Description
Summary:The use of protein–substrate binding to program the self‐assembly of nanoparticle‐based structures from aqueous solution is highlighted here. The systems discussed include aqueous dispersions of metal nanoparticles with surface‐attached antibodies and bivalent antigens in solution (see Figure), and ferritin‐encapsulated metal oxide nanoparticles with surface biotin groups and streptavidin in solution.
ISSN:0935-9648
1521-4095
DOI:10.1002/(SICI)1521-4095(200001)12:2<147::AID-ADMA147>3.0.CO;2-U