When meta-analyses get it wrong: response to 'treatment outcomes for anorexia nervosa: a systematic review and meta-analysis of randomized controlled trials'

[...]the broad range of time points used of EOT and the lack of robust follow-up data raise major questions about the outcomes reported at either time point. [...]the authors decided to include studies of treatment for both adolescents and adults with AN in the same meta-analysis. [...]using mean ag...

Full description

Saved in:
Bibliographic Details
Published in:Psychological medicine 2019-03, Vol.49 (4), p.697-698
Main Authors: Lock, James, Kraemer, Helena Chmura, Jo, Booil, Couturier, Jennifer
Format: Article
Language:English
Subjects:
Adolescents
Age
Anorexia
Clinical outcomes
Clinical trials
Eating disorders
Meta-analysis
Systematic review
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:[...]the broad range of time points used of EOT and the lack of robust follow-up data raise major questions about the outcomes reported at either time point. [...]the authors decided to include studies of treatment for both adolescents and adults with AN in the same meta-analysis. [...]using mean age as a moderator of effect at the study level is not the same as individual age as a moderator of treatment effect at the patient level, the long-known ‘ecological fallacy’. [...]including studies addressing the research question of interest that are grossly underpowered to detect clinically significant treatment effects slows progress to reaching a correct and definitive conclusion (Kraemer and Blasey, 2015). [...]most of the effect sizes included in the meta-analysis are derived from inadequately powered studies.
ISSN:0033-2917
1469-8978
DOI:10.1017/S003329171800329X