Metabolic syndrome, depression and anhedonia among young adults

•MetS was more prevalent among subjects with depression and anhedonia.•Subjects with depression and anhedonia have a worse metabolic profile.•Anhedonia may contribute to development of MetS. The aim of this study was to assess the association between anhedonia and metabolic syndrome (MetS) in a well...

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Bibliographic Details
Published in:Psychiatry research 2019-01, Vol.271, p.306-310
Main Authors: Moreira, Fernanda Pedrotti, Jansen, Karen, Cardoso, Taiane de Azevedo, Mondin, Thaíse Campos, Vieira, Igor Soares, Magalhães, Pedro Vieira da Silva, Kapczinski, Flavio, Souza, Luciano Dias de Mattos, da Silva, Ricardo Azevedo, Oses, Jean Pierre, Wiener, Carolina David
Format: Article
Language:English
Subjects:
Anhedonia
Depression
Metabolic syndrome
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Summary:•MetS was more prevalent among subjects with depression and anhedonia.•Subjects with depression and anhedonia have a worse metabolic profile.•Anhedonia may contribute to development of MetS. The aim of this study was to assess the association between anhedonia and metabolic syndrome (MetS) in a well-characterized community sample of individuals with a current depressive episode. This is a cross-sectional study with young adults aged 24–30 years old. Depressive episode and the presence of anhedonia was assessed using the Mini International Neuropsychiatric Interview – Plus version (MINI Plus). The MetS was assessed using the National Cholesterol Education Program Adult Treatment Panel III (NCEP/ATP III). The sample included 931 subjects, being 22 had depression without anhedonia, whereas 55 had depression with anhedonia. MetS was more prevalent among subjects with depression and anhedonia (43.6%) when compared to individuals without anhedonia and population control group. Moreover, subjects with depression and anhedonia have a significant increase of levels of glucose, triglycerides, total-cholesterol and LDL-cholesterol, as well as significant decreased in the HDL-cholesterol level. The present study showed that individuals with depression and anhedonia present higher prevalence of MetS. Our study suggests that the use of the concept of anhedonia may contribute to a better understanding of the complex relationship between depression and metabolic syndrome.
ISSN:0165-1781
1872-7123
DOI:10.1016/j.psychres.2018.08.009