Comparison of Laparoscopic and Open Approach in Treating Gallbladder Cancer

• Published in: The Journal of surgical research 2019-02, Vol.234, p.269-276
• Main Authors: Feng, Jia-Wei, Yang, Xing-Hai, Liu, Chi-Wen, Wu, Bao-Qiang, Sun, Dong-Lin, Chen, Xue-Min, Jiang, Yong, Qu, Zhen
• Format: Article
• Language: English
• Subjects: Gallbladder cancer; Laparoscopy; Prognosis; Radical gallbladder surgery
• ISSN: 0022-4804; 1095-8673
• DOI: 10.1016/j.jss.2018.09.025

Preliminary study on the feasibility and efficacy of laparoscopic cholecystectomy and radical cholecystectomy in stage Tis-T3 gallbladder cancer (GBC). Retrospective analysis of the clinical data of 102 patients with GBC from August 2008 to August 2017 in the Department of Hepatopancreatobiliary Surgery at the Third Affiliated Hospital of Soochow University. The clinical and pathological data of laparoscopic surgery and open surgery were compared. Of 102 patients with GBC, 41 underwent laparoscopic treatment, 12 of whom underwent laparoscopic cholecystectomy, and the others underwent laparoscopic radical cholecystectomy/extended radical cholecystectomy. Sixty-one patients underwent radical cholecystectomy/extended radical cholecystectomy. Based on the individual patient's condition, excision of the extrahepatic biliary tract and cholangioenterostomy were performed. There were no perioperative deaths. There was no significant difference in the operative blood loss (P = 0.732), operative time (P = 0.058), postoperative complications (P = 0.933), R0 margins (P = 0.679), and tumor-related death (P = 0.396) between the laparoscopic group and the laparotomy group. The postoperative activity time (P