Renal intraparenchymal resistive index: the ultrasonographic answer to many clinical questions

The use of renal resistive indices (RRIs) for the study of renal microcirculation has in the past been proposed for the identification of renal organ damage or even to specifically identify injury to some areas of the renal parenchyma. Nevertheless, according to the most recent evidences from litera...

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Bibliographic Details
Published in:Journal of nephrology 2019-08, Vol.32 (4), p.527-538
Main Authors: Di Nicolò, Pierpaolo, Granata, Antonio
Format: Article
Language:English
Subjects:
Medicine
Medicine & Public Health
Nephrology
Review
Urology
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Summary:The use of renal resistive indices (RRIs) for the study of renal microcirculation has in the past been proposed for the identification of renal organ damage or even to specifically identify injury to some areas of the renal parenchyma. Nevertheless, according to the most recent evidences from literature this organ-based conception of RRIs has been proven to be partial and unable to explain the RRIs variations in clinical settings of sepsis or combined organ failure of primitively extrarenal origin or, more generally, the deep connection between RRIs and hemodynamic factors such as compliance and pulsatility of the large vessels. The aim of this review is to explain the physiopathological basis of RRIs determination and the most common interpretative errors in their analysis. Moreover, through a comprehensive vision of these Doppler indices, the traditional and emerging clinical application fields for RRIs are discussed.
ISSN:1121-8428
1724-6059
DOI:10.1007/s40620-018-00567-x