Plant selenium toxicity: Proteome in the crosshairs

[Display omitted] The metalloid element, selenium (Se) is in many ways special and perhaps because of this its research in human and plant systems is of great interest. Despite its non-essentiality, higher plants take it up and metabolize it via sulfur pathways, but higher amounts of Se cause toxic...

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Bibliographic Details
Published in:Journal of plant physiology 2019-01, Vol.232, p.291-300
Main Authors: Kolbert, Z., Molnár, Á., Feigl, G., Van Hoewyk, D.
Format: Article
Language:English
Subjects:
Literature reviews
Molecular modelling
Nitroprotein
Oxyprotein
Phytotoxicity
Proteasomes
Protein biosynthesis
Protein synthesis
Proteins
Proteome
Proteomes
Selenium
Selenocysteine
Selenoprotein
Selenoproteins
Signs and symptoms
Sulfur
Toxicity
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Summary:[Display omitted] The metalloid element, selenium (Se) is in many ways special and perhaps because of this its research in human and plant systems is of great interest. Despite its non-essentiality, higher plants take it up and metabolize it via sulfur pathways, but higher amounts of Se cause toxic symptoms in plants. However, the molecular mechanisms of selenium phytotoxicity have been only partly revealed; the data obtained so far point out that Se toxicity targets the plant proteome. Besides seleno- and oxyproteins, nitroproteins are also formed due to Se stress. In order to minimize proteomic damages induced by Se, certain plants are able to redirect selenocysteine away from protein synthesis thus preventing Se-protein formation. Additionally, the damaged or malformed selenoproteins, oxyproteins and nitroproteins may be removed by proteasomes. Based on the literature this review sets Se toxicity mechanisms into a new concept and it draws attention to the importance of Se-induced protein-level changes.
ISSN:0176-1617
1618-1328
DOI:10.1016/j.jplph.2018.11.003