Chromoblastomycosis Caused by Fonsecaea nubica: First Report in Northern China and Literature Review

Chromoblastomycosis is found worldwide with higher incidence in tropical and subtropical regions. Fonsecaea spp. is one of the major causative agents of this disease. First case of chromoblastomycosis due to Fonsecaea nubica in Northern China is reported in a 75-year-old Chinese male. We firstly sum...

Full description

Saved in:
Bibliographic Details
Published in:Mycopathologia (1975) 2019-02, Vol.184 (1), p.97-105
Main Authors: You, Zimeng, Yang, Xiaoxiao, Yu, Jianbin, Zhang, Jiangan, Ran, Yuping
Format: Article
Language:English
Subjects:
Actin
Biomedical and Life Sciences
Cdc42 protein
Cell division
Chromomycosis
Chromosomal proteins
Eukaryotic Microbiology
Lactase
Lesions
Life Sciences
Literature reviews
Medical Microbiology
Microbial Ecology
Microbiology
Muscle proteins
Original Paper
Plant Sciences
Polyketide synthase
Spacer
Trauma
Tubulin
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Chromoblastomycosis is found worldwide with higher incidence in tropical and subtropical regions. Fonsecaea spp. is one of the major causative agents of this disease. First case of chromoblastomycosis due to Fonsecaea nubica in Northern China is reported in a 75-year-old Chinese male. We firstly summarized molecular identification methods of Fonsecaea spp. and all the strains of F. nubica reported in the literature. Sequencing of internal transcribed spacer alone and/or combined with actin ( ACT1 ), partial cell division cycle ( CDC42 ) and partial beta-tubulin ( BT2 ) were most commonly used to identify species, while lactase ( Lac ), homogentisate ( HmgA ) and polyketide synthase ( PKS1 ) were also used in some cases. Most strains were isolated from South America and Eastern China. Five clinical cases of chromoblastomycosis due to F. nubica from Asia and Europe were also reviewed. All the five patients were male, over 30 years old, and their lesions occurred after trauma.
ISSN:0301-486X
1573-0832
DOI:10.1007/s11046-018-0307-0