Loading…
Prognostic value of C‐reactive protein/albumin ratio for patients with hypopharyngeal and laryngeal cancer undergoing invasive surgery involving laryngectomy
Background The C‐reactive protein/albumin (CRP/Alb) ratio has been recently established as a prognostic indicator in various cancer types. However, few reports regarding the prognostic value of the CRP/Alb ratio in head and neck cancer exist. This study aimed to investigate the significance of the C...
Saved in:
| Published in: | Head & neck 2019-05, Vol.41 (5), p.1342-1350 |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c3535-7f9d06c76ea184a0be43f9fab81d938b438d0f1b14d03adec13872b38c6367853 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c3535-7f9d06c76ea184a0be43f9fab81d938b438d0f1b14d03adec13872b38c6367853 |
| container_end_page | 1350 |
| container_issue | 5 |
| container_start_page | 1342 |
| container_title | Head & neck |
| container_volume | 41 |
| creator | Kuboki, Akihito Kanaya, Hiroaki Nakayama, Tsuguhisa Konno, Wataru Goto, Kazutaka Nakajima, Itsuo Kashiwagi, Takashi Hirabayashi, Hideki Haruna, Shin‐ichi |
| description | Background
The C‐reactive protein/albumin (CRP/Alb) ratio has been recently established as a prognostic indicator in various cancer types. However, few reports regarding the prognostic value of the CRP/Alb ratio in head and neck cancer exist. This study aimed to investigate the significance of the CRP/Alb ratio in clinical outcomes after invasive surgery involving laryngectomy for hypopharyngeal and laryngeal cancer.
Methods
We evaluated 56 patients who underwent total laryngectomy or total pharyngolaryngectomy between 2003 and 2012. Univariate and multivariate analyses were retrospectively performed to examine the prognostic value of the CRP/Alb ratio in these patients.
Results
The optimal cutoff value of the CRP/Alb ratio was 0.32. Multivariate analysis showed that the CRP/Alb ratio was a significant and independent predictor of poor overall and disease‐free survival.
Conclusion
The CRP/Alb ratio may be a novel and useful indicator for predicting postoperative outcomes in patients with hypopharyngeal and laryngeal cancer. |
| doi_str_mv | 10.1002/hed.25565 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2157666895</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2209952252</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3535-7f9d06c76ea184a0be43f9fab81d938b438d0f1b14d03adec13872b38c6367853</originalsourceid><addsrcrecordid>eNp1kc9u1DAQhyNERUvhwAsgS1zgkK7_Js4RbQtFqtQe4Gw5ziTryrGDnWyVG4_AG_BuPAkJu-0BiZPH48-fZvTLsjcEXxCM6WYHzQUVohDPsjOCqzLHjJfP15qznOGSn2YvU7rHGLOC0xfZKcNCUMn5WfbrLobOhzRag_baTYBCi7a_f_yMoM1o94CGGEawfqNdPfXWo6hHG1AbIhqWCvyY0IMdd2g3D2HY6Tj7DrRD2jfIPd2M9gYimnwDsQvWd8j6vU6rP02xgzivjeD269PxmxlDP7_KTlrtErw-nufZt09XX7fX-c3t5y_bjze5YYKJvGyrBhemLEATyTWugbO2anUtSVMxWXMmG9ySmvAGM92AIUyWtGbSFKwopWDn2fuDd1n3-wRpVL1NBpzTHsKUFCWiLIpCViv67h_0PkzRL9MpSnFVCUoFXagPB8rEkFKEVg3R9stmimC1pqaW1NTf1Bb27dE41f3SfSQfY1qAzQF4sA7m_5vU9dXlQfkH5NemAg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2209952252</pqid></control><display><type>article</type><title>Prognostic value of C‐reactive protein/albumin ratio for patients with hypopharyngeal and laryngeal cancer undergoing invasive surgery involving laryngectomy</title><source>Wiley</source><creator>Kuboki, Akihito ; Kanaya, Hiroaki ; Nakayama, Tsuguhisa ; Konno, Wataru ; Goto, Kazutaka ; Nakajima, Itsuo ; Kashiwagi, Takashi ; Hirabayashi, Hideki ; Haruna, Shin‐ichi</creator><creatorcontrib>Kuboki, Akihito ; Kanaya, Hiroaki ; Nakayama, Tsuguhisa ; Konno, Wataru ; Goto, Kazutaka ; Nakajima, Itsuo ; Kashiwagi, Takashi ; Hirabayashi, Hideki ; Haruna, Shin‐ichi</creatorcontrib><description>Background
The C‐reactive protein/albumin (CRP/Alb) ratio has been recently established as a prognostic indicator in various cancer types. However, few reports regarding the prognostic value of the CRP/Alb ratio in head and neck cancer exist. This study aimed to investigate the significance of the CRP/Alb ratio in clinical outcomes after invasive surgery involving laryngectomy for hypopharyngeal and laryngeal cancer.
Methods
We evaluated 56 patients who underwent total laryngectomy or total pharyngolaryngectomy between 2003 and 2012. Univariate and multivariate analyses were retrospectively performed to examine the prognostic value of the CRP/Alb ratio in these patients.
Results
The optimal cutoff value of the CRP/Alb ratio was 0.32. Multivariate analysis showed that the CRP/Alb ratio was a significant and independent predictor of poor overall and disease‐free survival.
Conclusion
The CRP/Alb ratio may be a novel and useful indicator for predicting postoperative outcomes in patients with hypopharyngeal and laryngeal cancer.</description><identifier>ISSN: 1043-3074</identifier><identifier>EISSN: 1097-0347</identifier><identifier>DOI: 10.1002/hed.25565</identifier><identifier>PMID: 30552844</identifier><language>eng</language><publisher>Hoboken, USA: John Wiley & Sons, Inc</publisher><subject>Albumin ; C‐reactive protein/albumin ratio ; Head & neck cancer ; hypopharyngeal cancer ; Invasiveness ; Laryngeal cancer ; Multivariate analysis ; Neck ; postoperative survival ; prognostic factor ; Surgery ; Throat cancer</subject><ispartof>Head & neck, 2019-05, Vol.41 (5), p.1342-1350</ispartof><rights>2018 Wiley Periodicals, Inc.</rights><rights>2019 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3535-7f9d06c76ea184a0be43f9fab81d938b438d0f1b14d03adec13872b38c6367853</citedby><cites>FETCH-LOGICAL-c3535-7f9d06c76ea184a0be43f9fab81d938b438d0f1b14d03adec13872b38c6367853</cites><orcidid>0000-0003-4902-4794</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27915,27916</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30552844$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kuboki, Akihito</creatorcontrib><creatorcontrib>Kanaya, Hiroaki</creatorcontrib><creatorcontrib>Nakayama, Tsuguhisa</creatorcontrib><creatorcontrib>Konno, Wataru</creatorcontrib><creatorcontrib>Goto, Kazutaka</creatorcontrib><creatorcontrib>Nakajima, Itsuo</creatorcontrib><creatorcontrib>Kashiwagi, Takashi</creatorcontrib><creatorcontrib>Hirabayashi, Hideki</creatorcontrib><creatorcontrib>Haruna, Shin‐ichi</creatorcontrib><title>Prognostic value of C‐reactive protein/albumin ratio for patients with hypopharyngeal and laryngeal cancer undergoing invasive surgery involving laryngectomy</title><title>Head & neck</title><addtitle>Head Neck</addtitle><description>Background
The C‐reactive protein/albumin (CRP/Alb) ratio has been recently established as a prognostic indicator in various cancer types. However, few reports regarding the prognostic value of the CRP/Alb ratio in head and neck cancer exist. This study aimed to investigate the significance of the CRP/Alb ratio in clinical outcomes after invasive surgery involving laryngectomy for hypopharyngeal and laryngeal cancer.
Methods
We evaluated 56 patients who underwent total laryngectomy or total pharyngolaryngectomy between 2003 and 2012. Univariate and multivariate analyses were retrospectively performed to examine the prognostic value of the CRP/Alb ratio in these patients.
Results
The optimal cutoff value of the CRP/Alb ratio was 0.32. Multivariate analysis showed that the CRP/Alb ratio was a significant and independent predictor of poor overall and disease‐free survival.
Conclusion
The CRP/Alb ratio may be a novel and useful indicator for predicting postoperative outcomes in patients with hypopharyngeal and laryngeal cancer.</description><subject>Albumin</subject><subject>C‐reactive protein/albumin ratio</subject><subject>Head & neck cancer</subject><subject>hypopharyngeal cancer</subject><subject>Invasiveness</subject><subject>Laryngeal cancer</subject><subject>Multivariate analysis</subject><subject>Neck</subject><subject>postoperative survival</subject><subject>prognostic factor</subject><subject>Surgery</subject><subject>Throat cancer</subject><issn>1043-3074</issn><issn>1097-0347</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNp1kc9u1DAQhyNERUvhwAsgS1zgkK7_Js4RbQtFqtQe4Gw5ziTryrGDnWyVG4_AG_BuPAkJu-0BiZPH48-fZvTLsjcEXxCM6WYHzQUVohDPsjOCqzLHjJfP15qznOGSn2YvU7rHGLOC0xfZKcNCUMn5WfbrLobOhzRag_baTYBCi7a_f_yMoM1o94CGGEawfqNdPfXWo6hHG1AbIhqWCvyY0IMdd2g3D2HY6Tj7DrRD2jfIPd2M9gYimnwDsQvWd8j6vU6rP02xgzivjeD269PxmxlDP7_KTlrtErw-nufZt09XX7fX-c3t5y_bjze5YYKJvGyrBhemLEATyTWugbO2anUtSVMxWXMmG9ySmvAGM92AIUyWtGbSFKwopWDn2fuDd1n3-wRpVL1NBpzTHsKUFCWiLIpCViv67h_0PkzRL9MpSnFVCUoFXagPB8rEkFKEVg3R9stmimC1pqaW1NTf1Bb27dE41f3SfSQfY1qAzQF4sA7m_5vU9dXlQfkH5NemAg</recordid><startdate>201905</startdate><enddate>201905</enddate><creator>Kuboki, Akihito</creator><creator>Kanaya, Hiroaki</creator><creator>Nakayama, Tsuguhisa</creator><creator>Konno, Wataru</creator><creator>Goto, Kazutaka</creator><creator>Nakajima, Itsuo</creator><creator>Kashiwagi, Takashi</creator><creator>Hirabayashi, Hideki</creator><creator>Haruna, Shin‐ichi</creator><general>John Wiley & Sons, Inc</general><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TK</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4902-4794</orcidid></search><sort><creationdate>201905</creationdate><title>Prognostic value of C‐reactive protein/albumin ratio for patients with hypopharyngeal and laryngeal cancer undergoing invasive surgery involving laryngectomy</title><author>Kuboki, Akihito ; Kanaya, Hiroaki ; Nakayama, Tsuguhisa ; Konno, Wataru ; Goto, Kazutaka ; Nakajima, Itsuo ; Kashiwagi, Takashi ; Hirabayashi, Hideki ; Haruna, Shin‐ichi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3535-7f9d06c76ea184a0be43f9fab81d938b438d0f1b14d03adec13872b38c6367853</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Albumin</topic><topic>C‐reactive protein/albumin ratio</topic><topic>Head & neck cancer</topic><topic>hypopharyngeal cancer</topic><topic>Invasiveness</topic><topic>Laryngeal cancer</topic><topic>Multivariate analysis</topic><topic>Neck</topic><topic>postoperative survival</topic><topic>prognostic factor</topic><topic>Surgery</topic><topic>Throat cancer</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kuboki, Akihito</creatorcontrib><creatorcontrib>Kanaya, Hiroaki</creatorcontrib><creatorcontrib>Nakayama, Tsuguhisa</creatorcontrib><creatorcontrib>Konno, Wataru</creatorcontrib><creatorcontrib>Goto, Kazutaka</creatorcontrib><creatorcontrib>Nakajima, Itsuo</creatorcontrib><creatorcontrib>Kashiwagi, Takashi</creatorcontrib><creatorcontrib>Hirabayashi, Hideki</creatorcontrib><creatorcontrib>Haruna, Shin‐ichi</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Head & neck</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kuboki, Akihito</au><au>Kanaya, Hiroaki</au><au>Nakayama, Tsuguhisa</au><au>Konno, Wataru</au><au>Goto, Kazutaka</au><au>Nakajima, Itsuo</au><au>Kashiwagi, Takashi</au><au>Hirabayashi, Hideki</au><au>Haruna, Shin‐ichi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prognostic value of C‐reactive protein/albumin ratio for patients with hypopharyngeal and laryngeal cancer undergoing invasive surgery involving laryngectomy</atitle><jtitle>Head & neck</jtitle><addtitle>Head Neck</addtitle><date>2019-05</date><risdate>2019</risdate><volume>41</volume><issue>5</issue><spage>1342</spage><epage>1350</epage><pages>1342-1350</pages><issn>1043-3074</issn><eissn>1097-0347</eissn><abstract>Background
The C‐reactive protein/albumin (CRP/Alb) ratio has been recently established as a prognostic indicator in various cancer types. However, few reports regarding the prognostic value of the CRP/Alb ratio in head and neck cancer exist. This study aimed to investigate the significance of the CRP/Alb ratio in clinical outcomes after invasive surgery involving laryngectomy for hypopharyngeal and laryngeal cancer.
Methods
We evaluated 56 patients who underwent total laryngectomy or total pharyngolaryngectomy between 2003 and 2012. Univariate and multivariate analyses were retrospectively performed to examine the prognostic value of the CRP/Alb ratio in these patients.
Results
The optimal cutoff value of the CRP/Alb ratio was 0.32. Multivariate analysis showed that the CRP/Alb ratio was a significant and independent predictor of poor overall and disease‐free survival.
Conclusion
The CRP/Alb ratio may be a novel and useful indicator for predicting postoperative outcomes in patients with hypopharyngeal and laryngeal cancer.</abstract><cop>Hoboken, USA</cop><pub>John Wiley & Sons, Inc</pub><pmid>30552844</pmid><doi>10.1002/hed.25565</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0003-4902-4794</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1043-3074 |
| ispartof | Head & neck, 2019-05, Vol.41 (5), p.1342-1350 |
| issn | 1043-3074 1097-0347 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2157666895 |
| source | Wiley |
| subjects | Albumin C‐reactive protein/albumin ratio Head & neck cancer hypopharyngeal cancer Invasiveness Laryngeal cancer Multivariate analysis Neck postoperative survival prognostic factor Surgery Throat cancer |
| title | Prognostic value of C‐reactive protein/albumin ratio for patients with hypopharyngeal and laryngeal cancer undergoing invasive surgery involving laryngectomy |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T00%3A30%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prognostic%20value%20of%20C%E2%80%90reactive%20protein/albumin%20ratio%20for%20patients%20with%20hypopharyngeal%20and%20laryngeal%20cancer%20undergoing%20invasive%20surgery%20involving%20laryngectomy&rft.jtitle=Head%20&%20neck&rft.au=Kuboki,%20Akihito&rft.date=2019-05&rft.volume=41&rft.issue=5&rft.spage=1342&rft.epage=1350&rft.pages=1342-1350&rft.issn=1043-3074&rft.eissn=1097-0347&rft_id=info:doi/10.1002/hed.25565&rft_dat=%3Cproquest_cross%3E2209952252%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c3535-7f9d06c76ea184a0be43f9fab81d938b438d0f1b14d03adec13872b38c6367853%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2209952252&rft_id=info:pmid/30552844&rfr_iscdi=true |