Comparing patients’ prescribed, self-reported, and actual intake of supplemental eicosapentaenoic acid + docosahexaenoic acid

Dietary fish oil supplements containing the omega-3 polyunsaturated fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are frequently used for cardiovascular benefit. However, several factors may limit the intake of prescribed doses. The objective of this study is to compare th...

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Bibliographic Details
Published in:Journal of clinical lipidology 2019-01, Vol.13 (1), p.170-175
Main Authors: Backes, James M., Melton, Brittany L., Ruisinger, Janelle F., Burkhardt, Crystal D., Moriarty, Patrick M.
Format: Article
Language:English
Subjects:
Aged
Cross-Sectional Studies
Dietary Supplements
Docosahexaenoic Acids - therapeutic use
Drug dosage calculations [MeSH]
Drug Prescriptions
Eicosapentaenoic Acid - therapeutic use
Female
Fish Oils - therapeutic use
Fish oils [MeSH]
Humans
Information literacy [MeSH]
Male
Medication Adherence
Middle Aged
Nonprescription drugs [MeSH]
Omega-3 fatty acids [MeSH]
Patient Education as Topic
Self Report
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Summary:Dietary fish oil supplements containing the omega-3 polyunsaturated fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are frequently used for cardiovascular benefit. However, several factors may limit the intake of prescribed doses. The objective of this study is to compare the prescribed, patient self-reported, and actual intake of supplemental EPA + DHA doses in a lipid-specialty clinic and identify common barriers and influences to therapy. Seventy-six patients prescribed supplemental fish oil were randomly selected to participate in a 28-item cross-sectional survey for evaluating patient knowledge and intake of prescribed supplemental EPA + DHA doses. Self-reported data were collected during a follow-up clinic visit, whereas actual intake was determined when patients had access to their fish oil bottle. These data were compared with their chart-documented prescribed EPA + DHA dose. Many patients were well-educated and had attended the lipid-specialty clinic for approximately 2 years but only 28.9% were confident that they could accurately recall their daily EPA + DHA dose. There were statistically significant differences between the prescribed doses and patients’ self-reported doses (3600 mg vs 2750 mg, P = .014), as well as between prescribed doses and actual intake (3600 mg vs 1575 mg, P 
ISSN:1933-2874
1876-4789
DOI:10.1016/j.jacl.2018.11.005