Lung Function in Infants with Sickle Cell Anemia

Lung volumes and forced expiratory flows were evaluated in 22 infants with sickle cell anemia and compared with a control group. Forced expiratory flows showed significantly lower values in the sickle cell group. The majority of infants had normal lung function, and obstruction was the most common p...

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Bibliographic Details
Published in:The Journal of pediatrics 2019-04, Vol.207, p.252-254
Main Authors: Ivankovich, Danilo Turcato, Braga, Josefina Aparecida Pellegrini, Lanza, Fernanda de Córdoba, Solé, Dirceu, Wandalsen, Gustavo Falbo
Format: Article
Language:English
Subjects:
anemia
Anemia, Sickle Cell - complications
Anemia, Sickle Cell - metabolism
Anemia, Sickle Cell - physiopathology
Cross-Sectional Studies
Female
Follow-Up Studies
Forced Expiratory Volume - physiology
Functional Residual Capacity - physiology
Humans
Infant
Lung - physiopathology
Male
Oximetry
Prognosis
respiratory function tests
Respiratory Function Tests - methods
Respiratory Insufficiency - etiology
Respiratory Insufficiency - metabolism
Respiratory Insufficiency - physiopathology
sickle cell
Tidal Volume - physiology
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Summary:Lung volumes and forced expiratory flows were evaluated in 22 infants with sickle cell anemia and compared with a control group. Forced expiratory flows showed significantly lower values in the sickle cell group. The majority of infants had normal lung function, and obstruction was the most common pattern of abnormality.
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2018.11.036