Prediction of the varices needing treatment with non‐invasive tests in patients with compensated advanced chronic liver disease

Backgrounds & Aims The Baveno VI guidelines proposed criteria including liver stiffness (LS) and platelet count to avoid screening endoscopy in patients with compensated advanced chronic liver disease (cACLD). This study was performed to validate the Baveno IV criteria and to compare its diagnos...

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Bibliographic Details
Published in:Liver international 2019-06, Vol.39 (6), p.1071-1079
Main Authors: Lee, Han Ah, Kim, Seung Up, Seo, Yeon Seok, Lee, Young‐Sun, Kang, Seong Hee, Jung, Young Kul, Kim, Moon Young, Kim, Ji Hoon, Kim, Sang Gyune, Suk, Ki Tae, Jung, Soung Won, Jang, Jae Young, An, Hyonggin, Yim, Hyung Joon, Um, Soon Ho
Format: Article
Language:English
Subjects:
Confidence intervals
Criteria
Diagnostic systems
Endoscopy
Laboratory tests
Liver
Liver diseases
Model accuracy
platelet
Platelets
Predictions
prophylaxis
Spleen
Stiffness
transient elastography
Ultrasound
varices
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Summary:Backgrounds & Aims The Baveno VI guidelines proposed criteria including liver stiffness (LS) and platelet count to avoid screening endoscopy in patients with compensated advanced chronic liver disease (cACLD). This study was performed to validate the Baveno IV criteria and to compare its diagnostic accuracy with other non‐invasive models. Methods Patients with cACLD who underwent laboratory tests, upper gastrointestinal endoscopy and abdominal ultrasound within 6 months of transient elastography were included. Results A total of 1218 patients with cACLD were included. VNT occurred in 249 patients (20.4%). With the Baveno VI criteria, the VNT miss rate was 1.9% with a 25.7% saved endoscopy rate. Using two criteria of LS 110 × 109 cells/L or LS 120 × 109 cells/L, the saved endoscopy rate was 39.1% while maintaining the VNT miss rate
ISSN:1478-3223
1478-3231
DOI:10.1111/liv.14036