H2AFZ, RNF4 and NR4A1 loci are associated with boar semen quality by population association studies

Spermatogenesis is a complex process regulated by many genes. In this study, H2AFZ, RNF4 and NR4A1 genes were selected as candidate genes for boar semen quality traits based on their functions during spermatogenesis, and the associations of three loci (H2AFZ c.192 + 210-192 + 213delCGAT, RNF4 c.374 ...

Full description

Saved in:
Bibliographic Details
Published in:Animal biotechnology 2019-10, Vol.30 (4), p.311-316
Main Authors: Zhao, Liping, Ma, Changping, Song, Huibin, Feng, Yue, Li, Yang, Xia, Xuanyan, Li, Jialian, Li, Fenge
Format: Article
Language:English
Subjects:
Alleles
Animal populations
Animals
boars
Genes
Genetic Association Studies
Genetic Loci
Genotype
H2AFZ
Histones - genetics
Hogs
Loci
Male
NR4A1
Nuclear Proteins - genetics
Nuclear Receptor Subfamily 4, Group A, Member 1 - genetics
Polymorphism, Single Nucleotide
Population studies
RNF4
Semen
Semen Analysis
semen quality
Sperm
Sperm Count
Sperm Motility - genetics
Spermatogenesis
Spermatogenesis - genetics
Suidae
Swine - genetics
Transcription Factors - genetics
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Spermatogenesis is a complex process regulated by many genes. In this study, H2AFZ, RNF4 and NR4A1 genes were selected as candidate genes for boar semen quality traits based on their functions during spermatogenesis, and the associations of three loci (H2AFZ c.192 + 210-192 + 213delCGAT, RNF4 c.374 + 358 T > C and NR4A1 c.956 + 796 A > G) with sperm quality traits were analyzed in Duroc (n = 185), Large White (n = 87) and Landrace (n = 49) pig populations. The results showed H2AFZ c.192 + 210-192 + 213delCGAT AA boars produced 1.52% lower abnormal sperm rate (ASR) than AB boars in Landrace pigs (p 
ISSN:1049-5398
1532-2378
DOI:10.1080/10495398.2018.1521825