Reproducibility and reliability of retinal and optic disc measurements obtained with swept-source optical coherence tomography in a healthy population

Purpose To analyze the reproducibility of macular and peripapillary thickness measurements, and optic nerve morphometric data obtained with Triton Optical coherence tomography (OCT) in a healthy population. Study design Observational cross sectional study. Material and methods A total of 108 eyes un...

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Bibliographic Details
Published in:Japanese journal of ophthalmology 2019-03, Vol.63 (2), p.165-171
Main Authors: Satue, Maria, Gavin, Alicia, Orduna, Elvira, Vilades, Elisa, Rodrigo, Maria Jesus, Obis, Javier, Polo, Vicente, Larrosa, Jose Manuel, Pablo, Luis Emilio, Garcia-Martin, Elena
Format: Article
Language:English
Subjects:
Clinical Investigation
Coefficient of variation
Correlation analysis
Eye (anatomy)
Mathematical analysis
Medicine
Medicine & Public Health
Ophthalmology
Optic nerve
Optical Coherence Tomography
Optics
Parameters
Population studies
Reproducibility
Retina
Thickness measurement
Tomography
Triton
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Summary:Purpose To analyze the reproducibility of macular and peripapillary thickness measurements, and optic nerve morphometric data obtained with Triton Optical coherence tomography (OCT) in a healthy population. Study design Observational cross sectional study. Material and methods A total of 108 eyes underwent evaluation using the Triton Swept Source-OCT. A wide protocol was used and measurements in each eye were repeated three times. Morphometric data of the optic nerve head, full macular thickness, ganglion cell layer (GCL) and retinal nerve fiber layer thickness (RNFL) were analyzed. For each parameter, the coefficient of variation (COV) and the intra-class (ICC) correlation values were calculated. Results Measurements were highly reproducible for all morphometric measurements of the optic disc, with a mean COV of 6.36%. Macular full thickness showed good COV and ICC coefficients, with a mean COV value of 1.00%. Macular GCL thickness showed a mean COV value of 3.06%, and ICC higher than 0.787. Peripapillary RNFL thickness showed good COV and ICC coefficients, with a mean COV value of 8.31% and ICC higher than 0.684. The inferotemporal sector showed the lowest ICC (0.685). Conclusions Triton OCT presents good reproducibility values in measurements corresponding to retinal parameters, with macular measurements showing the highest reproducibility rates. Peripapillary RNFL measurements should be evaluated with caution.
ISSN:0021-5155
1613-2246
DOI:10.1007/s10384-018-00647-2